Evidence map›Paper›PMID 39046598›Full record

ArticleJournal of neuro-oncology2024

Frequency of and risk factors associated with local recurrence after spinal stereotactic body radiation therapy without surgery.

Hidetoshi Shimizu, Yutaro Koide, Shoichi Haimoto, Takahiro Aoyama, Hiroyuki Tachibana, Shingo Hashimoto, Tohru Iwata, Tomoki Kitagawa, Takeshi Kodaira

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Article in Journal of neuro-oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hidetoshi ShimizuDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan. hishimizu@aichi-cc.jp.ORCID http://orcid.org/0000-0002-6633-0964
Yutaro KoideDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Shoichi HaimotoDepartment of Neurosurgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Takahiro AoyamaDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Hiroyuki TachibanaDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Shingo HashimotoDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Tohru IwataDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Tomoki KitagawaDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
Takeshi KodairaDepartment of Radiation Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.

Funding

Japan Society for the Promotion of Science 24K18847
6 · The paper itself

Abstract

purposeThis study aimed to identify factors associated with local recurrence after spinal stereotactic body radiation therapy (SBRT), focusing on patient movement during treatment and tumor characteristics.

methodsA total of 48 patients who underwent spinal SBRT alone without surgery from August 2017 to October 2022 were evaluated. Logistic regression analysis was conducted to identify factors associated with local recurrence, including patient movement and tumor characteristics such as soft tissue involvement and tumor volume. Patient movement during treatment was measured using cone beam computed tomography before and after irradiation.

resultsAmong the included cases, 68.7% and 42.6% had soft tissue involvement and movement exceeding 1 mm, respectively. The median follow-up duration for local recurrence was 11.6 (range: 0.7-44.9) months, whereas the median duration to local recurrence was 6.3 months. Within 12 months, 29.3% of the patients experienced local recurrence, among whom 43.9% moved ≥ 1 mm during treatment, whereas 15.8% did not move. Univariable analysis found that both soft tissue involvement (OR = 10.3, 1.21-87.9; p = 0.033) and patient movement ≥ 1 mm (OR = 5.75, 1.45-22.8; p = 0.013) were associated with local recurrence. Multivariable analysis identified patient movement as an independent prognostic factor for local recurrence (OR = 5.15, 1.06-25.0; p = 0.042).

conclusionOur results suggest that patient movement during spinal SBRT was associated with local recurrence, emphasizing the need for better immobilization techniques and shorter delivery times to improve tumor control.

Indexed as

Neoplasm Recurrence, LocalRadiosurgerySpinal NeoplasmsAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsLocal recurrencePatient movementSBRTSpineStereotactic body radiation therapy

Identifiers

PMID39046598

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