ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2024
Optical quality in vitro and in vivo of an extended depth-of-focus intraocular lens with isofocal design.
Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Visual Quality and Symptomatology Following Implantation of a Non-Diffractive Extended Depth-of-Focus Intraocular Lens.Journal of clinical medicine · 2025Article
- Visual and Refractive Outcomes After Implantation of an Isofocal Optic-Design Intraocular Lens with Double C-Loop Haptics in Japanese Eyes.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Clinical Outcomes of a Multicenter Study Following Implantation of an Isofocal Optic IOL with Double C-Loop Haptics.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study is to compare optical quality results obtained in laboratory analysis (in vitro) versus clinical data (in vivo).
methodsThe optical quality of ISOPure intraocular lens was assessed both in vitro and in vivo using the modulation transfer function (MTF) for 3.0 and 4.5 mm pupil diameters. In vitro measurements were obtained using deflectometer NIMO TRF1504, while in vivo measurements were taken with OPD-Scan III in a set of patients implanted with this lens. Ray tracing techniques were used to determine the MTF and area under MTF curve (MTFa) from the measured wavefront for the isolated lens and for the whole eye.
resultsThe MTF of the isolated lens obtained under both in vitro and in vivo conditions showed comparable results for both pupil sizes. However, differences were found when comparing the MTF of the whole eye with the lens implanted versus the MTF measured in vitro for 4.5 mm pupil size. Also, the MTFa defocus curve was compared with the defocus curve measured in vivo.
conclusionThe defocus curve from the in vivo study aligns closely with the MTFa of the in vitro model, with a useful defocus range of 0.40D. Thus, it is possible to anticipate the visual results of the implanted isofocal lens by using measurements on an optical bench and conducting optical simulations.
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Registered trials
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