ArticleAbdominal radiology (New York)2025
Diagnostic performance of Node-RADS score for mesorectal lymph node metastasis in rectal cancer.
Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Diagnostic accuracy of Node-RADS for lymph node metastasis in rectal cancer: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Development and validation of an interpretable MRI-based multimodal fusion model for predicting lymph node metastasis after neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a multicenter study.Abdominal radiology (New York) · 2026Article
- CT-based Node-RADS classification in the assessment of rectal cancer: diagnostic performance and postoperative prognostic stratification.BMC cancer · 2026Article
- Node-RADS in cervical cancer: a multi-reader agreement and diagnostic performance study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026Article
- A head-to-head comparison of MRI and CT using Node-RADS for rectal cancer lymph nodes: Observer agreement and diagnostic performance.European journal of radiology open · 2026Article
- MRI to guide clinical management of rectal cancer: updated consensus recommendations from the European Society of Gastrointestinal and Abdominal Radiology (ESGAR)-PART I primary staging.European radiology · 2026Article
- Node-RADS for preoperative locoregional nodal staging of endometrial cancer: reproducibility and accuracy assessment using CT and MRI.European radiology · 2026Article
- Diagnostic performance of node-RADS classification for primary lymph node assessment in rectal cancer: a modality benchmarking study.Journal of cancer research and clinical oncology · 2025Article
- Node Reporting and Data System 1.0 (Node-RADS) for the Assessment of Oncological Patients' Lymph Nodes in Clinical Imaging.Journal of clinical medicine · 2025Review
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12 authors.
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Abstract
purposeTo explore the diagnostic performance of the Node-RADS scoring system on preoperative assessment of mesorectal lymph node metastasis (LNM) status in rectal cancer, in comparison with the ESGAR category and size of lymph node (LN).
methodsPreoperative clinical and MRI data of 154 rectal adenocarcinoma patients treated with radical resection surgery were retrospectively analyzed. The differences in the clinical, pathological and imaging characteristics between the pN- and pN + groups were surveyed. The correlations of Node-RADS score and ESGAR category to pN stage, LNM number and lymph node ratio (LNR) were investigated. The performances on assessing pathological LNM were compared among individual approaches. A nomogram combined the imaging and clinical features was also established and evaluated.
resultsSignificant differences in CEA, tumor maximum diameter, tumor location, LN short-axis diameter, Node-RADS score and ESGAR category were found between the pN- and pN + groups. Node-RADS correlated significantly with pN stage, LNM number, and LNR (r = 0.665, 0.685, and 0.675, p < 0.001). Node-RADS had the highest AUC (0.862) for predicting pN + status, surpassing ESGAR (AUC = 0.797, p = 0.040) and LN size (AUC = 0.762, p = 0.015). The nomogram had the best diagnostic performance (AUC = 0.901), significantly outperforming Node-RADS alone (p = 0.037).
conclusionsThe Node-RADS scoring system is comparable to the ESGAR category and surpasses short-axis diameter in preoperatively predicting LNM in rectal cancer. Integrating imaging and clinical features will lead to an enhancement in diagnostic performance. Moreover, a clear relationship was demonstrated between the Node-RADS score and the quantity-dependent pathological characteristics of LNM.
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