Evidence map›Paper›PMID 39046474›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Managing medically refractory elevated intracranial pressure in a pediatric patient on ECMO: illustrative case.

Tirone Young, Bahie Ezzat, Noah Nichols, Scott Aydin, Peter Pastuszko, Peter F Morgenstern

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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tirone YoungDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Bahie EzzatDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Noah NicholsDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Scott AydinDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter PastuszkoDepartment of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Peter F MorgensternDepartment of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. peter.morgenstern@mountsinai.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe demonstrate the complexities of managing pediatric patients on extracorporeal membrane oxygenation (ECMO) therapy requiring neurosurgery, focusing on systemic anticoagulation, cardiac function, and medically refractory intracranial pressure (ICP).

methodsA 3.5-year-old female with Tetralogy of Fallot developed severe ischemic cerebral edema following post-operative cardiac arrest and required ECMO. This case, along with four additional cases of children requiring neurosurgery while on ECMO, was examined.

resultsEmergency neurosurgical intervention in the primary case led to significant improvement, highlighting the delicate balance between managing ECMO-induced anticoagulation and urgent neurosurgical needs. The additional cases had variable outcomes, emphasizing the challenges of caring for these critically ill patients.

conclusionSuccessful management of children requiring ECMO support and neurosurgical intervention requires thoughtful multidisciplinary care. This report illustrates some of the nuances in such decision-making, and demonstrates one potential path to a good outcome.

Indexed as

Extracorporeal Membrane OxygenationIntracranial HypertensionChild, PreschoolFemaleHeart ArrestHumansNeurosurgical ProceduresTetralogy of FallotAnticoagulation managementCongenital heart diseaseCraniectomyECMO

Identifiers

PMID39046474

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.