Evidence map›Paper›PMID 39046350›Full record

ArticleThe New England journal of medicine2024

Features of HIV Infection in the Context of Long-Acting Cabotegravir Preexposure Prophylaxis.

Raphael J Landovitz, Sinead Delany-Moretlwe, Jessica M Fogel, Mark A Marzinke, Estelle Piwowar-Manning, Paul Richardson, Elias K Halvas, John W Mellors, Deborah Persaud, Ryan Kofron and 11 more

Abstract readLetter
In one paragraph

Article in The New England journal of medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  2. Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  3. Article
  4. Article
  5. Review
  6. Prospective HIV RNA screening with long-acting cabotegravir pre-exposure prophylaxis in HPTN 083.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. HIV-1 testing in the context of expanding PrEP modalities.Journal of the International AIDS Society · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Preventing HIV in women in Africa.Nature medicine · 2025
    Review
  16. Article
  17. Article
  18. Nucleic acid amplification testing using dried blood spots to confirm the diagnosis of HIV-1 in adults.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2024
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Raphael J LandovitzUniversity of California, Los Angeles, Los Angeles, CA rlandovitz@mednet.ucla.edu.
Sinead Delany-MoretlweUniversity of the Witwatersrand, Johannesburg, South Africa.
Jessica M FogelJohns Hopkins University, Baltimore, MD.
Mark A MarzinkeJohns Hopkins University, Baltimore, MD.
Estelle Piwowar-ManningJohns Hopkins University, Baltimore, MD.
Paul RichardsonJohns Hopkins University, Baltimore, MD.
Elias K HalvasUniversity of Pittsburgh, Pittsburgh, PA.
John W MellorsUniversity of Pittsburgh, Pittsburgh, PA.
Deborah PersaudJohns Hopkins University, Baltimore, MD.
Ryan KofronUniversity of California, Los Angeles, Los Angeles, CA.
Marybeth McCauleyFHI 360, Durham, NC.
Scott RoseFHI 360, Durham, NC.
Alex R RinehartViiV Healthcare, Research Triangle Park, NC.
James F RooneyGilead Sciences, Foster City, CA.
Adeola AdeyeyeNational Institutes of Health, Bethesda, MD.
Myron S CohenUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
Deborah DonnellFred Hutchinson Cancer Center, Seattle, WA.
Mina C HosseinipourUniversity of North Carolina at Chapel Hill, Chapel Hill, NC.
Beatriz GrinsztejnInstituto de Pesquisa Clinica Evandro Chagas-Fiocruz, Rio de Janeiro, Brazil.
Susan H EshlemanJohns Hopkins University, Baltimore, MD.
HPTN 083 and 084 Study Teams

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI MYRON Scott COHEN, Sinead Delany-Moretlwe · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
HIV Prevention trials Network (HPTN) Coordinating and Operations CenterU01AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI VERMUND, STEN H. · 2006 to 2010
$72.7M
UCLA AIDS Prevention and Treatment Clinical Trials UnitUM1AI069424 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Judith S. Currier, RAPHAEL J LANDOVITZ · 2012 to 2026
$51.8M
Wits HIV Research Group CLINICAL TRIAL UNIT (CTU) reapplicationUM1AI069463 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI REES, HELEN, SANNE, IAN MATTHIAS · 2012 to 2025
$31.8M
Units for HIV/AIDS Clinical Trials NetworksU01AI069463 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI SANNE, IAN MATTHIAS · 2007 to 2011
$24.2M
NIAID NIH HHS U01 AI068619NIAID NIH HHS U01 AI069463NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NIAID NIH HHS UM1 AI069424NIAID NIH HHS UM1 AI069463
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39046350
PMCPMC11598663

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.