Evidence map›Paper›PMID 39046060›Full record

ArticleCritical care science2024

Analysis of factors associated with admission to the intensive care unit of children and adolescents with COVID-19: application of a multilevel model.

Lecidamia Cristina Leite Damascena, Aline Roseane Queiroz de Paiva Faria, Nyellisonn Nando Nóbrega de Lucena, Ana Hermínia Andrade E Silva, Talita Tavares Alves de Almeida, Diana de Fátima Alves Pinto, Hemílio Fernandes Campos Coêlho, Ana Maria Gondim Valença

Abstract read
In one paragraph

Article in Critical care science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lecidamia Cristina Leite DamascenaPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-2128-4757
Aline Roseane Queiroz de Paiva FariaPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-8737-953X
Nyellisonn Nando Nóbrega de LucenaPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-6524-0908
Ana Hermínia Andrade E SilvaPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-4806-2206
Talita Tavares Alves de AlmeidaSecretaria de Saúde do Estado da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-1388-7996
Diana de Fátima Alves PintoSecretaria de Saúde do Estado da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-5958-6216
Hemílio Fernandes Campos CoêlhoPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0002-7140-3590
Ana Maria Gondim ValençaPostgraduate Program in Decision Models and Health, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - João Pessoa (PB), Brazil.ORCID http://orcid.org/0000-0001-8460-3981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify factors associated with hospitalization in the intensive care unit in children and adolescents with COVID-19.

methodsThis was a retrospective cohort study using secondary data of hospitalized children and adolescents (zero to 18 years old) with COVID-19 reported in Paraíba from April 2020 to July 2021, totaling 486 records. Descriptive analysis, logistic regression and multilevel regression were performed, utilizing a significance level of 5%.

resultsAccording to logistic regression without hierarchical levels, there was an increased chance of admission to the intensive care unit for male patients (OR = 1.98; 95%CI 1.18 - 3.32), patients with respiratory distress (OR = 2.43; 95%CI 1.29 - 4.56), patients with dyspnea (OR = 3.57; 95%CI 1.77 - 7.18) and patients living in large cities (OR = 2.70; 95%CI 1.07 - 6.77). The likelihood of requiring intensive care was observed to decrease with increasing age (OR = 0.94; 95%CI = 0.90 - 0.97), the presence of cough (OR = 0.32; 95%CI 0.18 - 0.59) or fever (OR = 0.42; 95%CI 0.23 - 0.74) and increasing Gini index (OR = 0.003; 95%CI 0.000 - 0.243). According to the multilevel analysis, the odds of admission to the intensive care unit increased in male patients (OR = 1.70; 95%CI = 1.68-1.71) and with increasing population size of the municipality per 100,000 inhabitants (OR = 1.01; 95%CI 1.01-1.03); additionally, the odds of admission to the intensive care unit decreased for mixed-race versus non-brown-skinned patients (OR = 0.981; 95%CI 0.97 - 0.99) and increasing Gini index (OR = 0.02; 95%CI 0.02 - 0.02).

conclusionThe effects of patient characteristics and social context on the need for intensive care in children and adolescents with SARS-CoV-2 infection were better estimated with the inclusion of a multilevel regression model.

Indexed as

COVID-19Intensive Care UnitsAdolescentAge FactorsChildChild, PreschoolFemaleHospitalizationHumansInfantInfant, NewbornLogistic ModelsMaleMultilevel AnalysisRetrospective StudiesRisk Factors

Identifiers

PMID39046060
PMCPMC11239204

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.