Evidence map›Paper›PMID 39045960›Full record

Trial reportRevista da Associacao Medica Brasileira (1992)2024

Effect of Cymbopogon olivieri-based herbal vaginal product on bacterial vaginosis.

Mitra Esmaili, Zarrin Sarhadynejad, Zohreh Salari, Tania Dehesh, Mahdiyeh Lashkarizadeh, Haleh Tajadini, Mohadese Kamali

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Revista da Associacao Medica Brasileira (1992), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mitra EsmailiKerman University of Medical Sciences, Faculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Medicine - Kerman, Iran.ORCID http://orcid.org/0000-0002-8262-5156
Zarrin SarhadynejadKerman University of Medical Sciences, Faculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Pharmacy - Kerman, Iran.ORCID http://orcid.org/0000-0001-5685-4054
Zohreh SalariKerman University of Medical Sciences, Afzalipour School of Medicine, Obstetrics and Gynecology Center - Kerman, Iran.ORCID http://orcid.org/0000-0002-8899-5350
Tania DeheshKerman University of Medical Sciences, School of Public Health, Department of Biostatistics and Epidemiology - Kerman, Iran.ORCID http://orcid.org/0000-0003-0083-0672
Mahdiyeh LashkarizadehKerman University of Medical Sciences, School of Medicine, Department of Pathology and Stem Cell Research Center - Kerman, Iran.ORCID http://orcid.org/0000-0002-5282-1252
Haleh TajadiniKerman University of Medical Sciences, Faculty of Persian Medicine, Medical Mycology and Bacteriology Research Center, Department of Traditional Medicine - Kerman, Iran.ORCID http://orcid.org/0000-0002-9125-684X
Mohadese KamaliKerman University of Medical Sciences, Faculty of Persian Medicine, Herbal and Traditional Medicines Research Center, Department of Traditional Medicine - Kerman, Iran.ORCID http://orcid.org/0000-0003-3227-3997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveBacterial vaginosis is the most common vaginal infection in reproductive-age women. If it is not treated, the quality of life will be reduced. In this study, the herbal medicine product Cymbopogon olivieri was used for its treatment.

methodsThis study was conducted with 90 women. The patients were randomly divided into two groups of 45: Cymbopogon olivieri and metronidazole. The treatment period was 7 days for each group. Improvement status was determined by eliminating at least three out of four of Amsel's criteria. A new variable with two order levels (negative and positive) was constructed. This new variable shows the status of the treatment process. Chi-square and Fisher's exact tests were used to examine the relationship between the new variable and treatment status.

resultsThe results demonstrate that Cymbopogon olivieri and metronidazole significantly reduced the burning, itching, malodor, abnormal vaginal discharge, pH, clue cell, and positive whiff test (p<0.05). The findings also demonstrate that neither treatment was statistically different from the other for at least three of Amsel's criteria.

conclusionThis study shows that the effect of Cymbopogon olivieri on bacterial vaginosis is similar to that of metronidazole. Hence, Cymbopogon olivieri is a suitable option to treat bacterial vaginosis.

Indexed as

CymbopogonMetronidazoleVaginosis, BacterialAdministration, IntravaginalAdultAnti-Bacterial AgentsFemaleHumansPhytotherapyTreatment OutcomeYoung AdultAnti-Bacterial AgentsMetronidazole

Identifiers

PMID39045960
PMCPMC11288269

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.