Evidence map›Paper›PMID 39045727›Full record

SynthesisOtolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2024

Long-Term Hearing Outcome For Vestibular Schwannomas After Microsurgery And Radiotherapy: A Systematic Review and Meta-Analysis.

Antonio Daloiso, Diego Cazzador, Stefano Concheri, Giulia Tealdo, Elisabetta Zanoletti

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonio DaloisoDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.ORCID 0000-0002-3687-8814
Diego CazzadorDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.ORCID 0000-0001-7272-7469
Stefano ConcheriDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.ORCID 0009-0001-0143-3751
Giulia TealdoDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.ORCID 0000-0003-3625-1568
Elisabetta ZanolettiDepartment of Neuroscience DNS, Otolaryngology Section, University of Padova, Padova, Italy.ORCID 0000-0001-5562-5292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHearing loss is a common symptom associated with vestibular schwannoma (VS), either because of the tumor's effects on the cochlear nerve or due to active treatments such as surgery or stereotactic radiosurgery (SRS). Treatment decisions for VS are based on factors including tumor size, hearing status, patient symptoms, and institutional preference. The study aimed to investigate long-term auditory outcomes in VS patients undergoing active treatments with a hearing preservation intent. DATA SOURCES: A systematic literature review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, searching Scopus, Pubmed, and Web of Science databases from inception to January 2024. REVIEW

methodsStudies meeting inclusion criteria, including a minimum 5-year follow-up and assessment of pre- and posttreatment hearing outcomes, were included. Pooled prevalence estimates for serviceable hearing after SRS and microsurgery were calculated using MetaXL software. Risk of bias assessment was performed with the Risk of Bias in Non-randomized Studies of Interventions tool.

resultsNine studies met the inclusion criteria, with 356 patients included for analysis. The pooled prevalence of maintaining serviceable hearing after SRS at 10 years was 18.1% (95% confidence interval [CI]: 1.7%-43.3%), with wide prediction intervals indicating variability in outcomes. Microsurgery demonstrated a higher prevalence of maintaining long-term serviceable hearing, with a pooled estimate of 74.5% (95% CI: 63.5%-84.1%).

conclusionThis systematic review underscores the importance of long-term follow-up in evaluating auditory outcomes in VS treatment. Despite the biases inherent to pretreatment patients selection, hearing preservation microsurgery for sporadic VS removal demonstrated favorable and stable long-term serviceable hearing.

Indexed as

Hearing LossMicrosurgeryNeuroma, AcousticRadiosurgeryHearingHumansTreatment Outcomeacoustic neuromahearing losshearing preservationmeta‐analysismicrosurgeryradiosurgerystereotactic radiotherapysystematic reviewvestibular schwannoma

Identifiers

PMID39045727
PMCPMC11605020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.