ReviewEuropean heart journal. Imaging methods and practice2024
Paravalvular regurgitation after transcatheter aortic valve replacement: incidence, quantification, and prognostic impact.
Review in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Impact of Early Nonfatal Complications After Transcatheter Aortic Valve Implantation on 1-Year Mortality and Quality of Life: Insights From the LANDMARK Trial.Structural heart : the journal of the Heart Team · 2026Article
- Pacemaker Implantation in Patients With Pre-Existing Bundle Branch Block Undergoing Balloon-Expandable Transcatheter Aortic Valve Replacement.Structural heart : the journal of the Heart Team · 2026Article
- Early Echocardiographic Changes Following Transcatheter Aortic Valve Implantation: A Comparative Analysis of Different Transcatheter Aortic Valve Systems.Journal of cardiovascular development and disease · 2026Article
- Transcatheter Paravalvular Leak Closure: A Step-by-Step Guide.Journal of cardiovascular development and disease · 2026Review
- Relationship between perioperative serum albumin levels and paravalvular leak after transcatheter aortic valve replacement.BMC cardiovascular disorders · 2026Observational
- Ultra-low-contrast transfemoral TAVI using the MyVal transcatheter heart valve: a prospective single-center feasibility and safety study.Frontiers in cardiovascular medicine · 2026Article
- Paravalvular Leak After Transcatheter Aortic Valve Replacement (TAVR): A Literature Review.Journal of clinical medicine · 2025Review
- Quantitative videodensitometric assessment of aortic regurgitation in Myval, Sapien, and Evolut THV series: Results from the LANDMARK trial.International journal of cardiology. Heart & vasculature · 2025Article
- Construct validity of automated assessment of invasively measured hemodynamics during transcatheter aortic valve replacement.European heart journal. Digital health · 2025Article
- Long-Term Outcomes of Mild Paravalvular Leak Following Transcatheter Aortic Valve Replacement.Structural heart : the journal of the Heart Team · 2025Article
- Impact of aortic landing zone geometry on TAVI implantation depth: comparison between ACURATEOpen heart · 2025Article
- Paravalvular Leak in Transcatheter Aortic Valve Implantation: A Review of Current Challenges and Future Directions.Journal of cardiovascular development and disease · 2025Review
- [Advances in stroke after transcatheter aortic valve replacement].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2025Review
- Paravalvular Leak After Transcatheter Aortic Valve Implantation: Importance of Preprocedural Variables and Intraprocedural Assessment.Journal of the American Heart Association · 2024Article
- Issue at a glance.European heart journal. Imaging methods and practice · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transcatheter aortic valve replacement (TAVR) is the standard of care in aortic stenosis with results comparable to surgical aortic valve replacement. However, paravalvular regurgitation (PVR) is more common after TAVR. With the alteration of devices and implantation techniques, the incidence of moderate or more PVR has declined. Mild PVR is still common in around 30% of TAVR patients in low-risk trials. Progression of AS causes myocardial hypertrophy and varying degrees of diastolic dysfunction which may cause heart failure even in combination with small volumes of PVR. Any degree of PVR is associated with an increased risk of overall and cardiovascular mortality. Predictors of PVR are annular eccentricity, severe calcification of the aortic valve, bicuspid aortic valves, and type of prosthesis where balloon-expandable devices are associated with less PVR. PVR is diagnosed using echocardiography, aortic angiogram with or without videodensitometry, haemodynamic parameters, or cardiac magnetic resonance. PVR can be treated using post-dilation, interventional treatment using a vascular plug, or implantation of a second device. Successful post-dilation depends on balloon size which should at least be equal to or >95% of the mean annulus diameter. Implantation of a second device to reduce PVR is successful in ∼90% of cases, either through lengthening of the sealing skirt in case of inadequate position or through further expansion of the index device. Implantation of a vascular plug can successfully reduce PVR and reduce mortality.
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