Evidence map›Paper›PMID 39045464›Full record

ArticleEuropean heart journal. Imaging methods and practice2024

The influence of transcatheter aortic valve replacement on left atrial mechanics: a systematic review and meta-analysis.

Thomas Meredith, Lauren Brown, Farhan Mohammed, Amy Pomeroy, David Roy, David W M Muller, Christopher Hayward, Michael Feneley, Mayooran Namasivayam

Abstract read
In one paragraph

Article in European heart journal. Imaging methods and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Issue at a glance.European heart journal. Imaging methods and practice · 2024
    Article
  3. Hydraulic forces assist left ventricular filling in aortic stenosis at baseline and after valve replacement.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas MeredithDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.ORCID https://orcid.org/0000-0002-6933-3714
Lauren BrownFaculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2050, Australia.
Farhan MohammedVictor Chang Cardiac Research Institute, 405 Liverpool Street, Darlinghurst, NSW 2010, Australia.
Amy PomeroyVictor Chang Cardiac Research Institute, 405 Liverpool Street, Darlinghurst, NSW 2010, Australia.
David RoyDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.
David W M MullerDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.
Christopher HaywardDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.ORCID https://orcid.org/0000-0003-4036-1890
Michael FeneleyDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.
Mayooran NamasivayamDepartment of Cardiology, St Vincent's Hospital, Level 4, Xavier Building, 438 Victoria Street, Darlinghurst, NSW 2010, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The morphology and function of the left atrium (LA) are intimately tied to left ventricular loading conditions. Data pertaining to the effect of transcatheter aortic valve replacement (TAVR) on LA function and geometry are scarce. The aim of the study was to quantify associations between TAVR and LA remodelling by pooling available data from published observational studies. Methods and results: A systematic review and meta-analysis were performed. Studies reporting serial LA speckle-tracking echocardiographic (STE) data, before and after TAVR, were included. Other outcome data included LA area and indexed volume (LAVi) and standard chamber measurements. Outcomes were stratified by timing of follow-up echocardiography: early (<6 months) or late (≥6 months). Twelve studies were included, comprising 1066 patients. The mean reduction in LAVi was 2.72 mL/m Conclusion: TAVR is associated with significant negative LA remodelling, and an improvement in LA mechanics, quantified by STE. The prognostic implications of these findings require further study.

Indexed as

aortic stenosisleft atrial functionleft atriumstraintranscatheter aortic valve replacement

Identifiers

PMID39045464
PMCPMC11195759

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.