ArticleFrontiers in genetics2024
Genetic correlation and causal relationship between sleep and myopia: a mendelian randomization study.
Article in Frontiers in genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Circadian rhythms regulate refractive development across species.bioRxiv : the preprint server for biology · 2026Article
- Mendelian Randomization Studies of Myopia: Choosing the Right Summary Statistics.Investigative ophthalmology & visual science · 2025Article
- Exploring causal relationship of traumatic brain injury and comorbidities: A Mendelian randomization study.Journal of Alzheimer's disease reports · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Purpose: To investigate the genetic correlation and causal links between sleep traits (including sleep duration, chronotype, and insomnia) and myopia. Methods: Summary data on three sleep traits (sleep duration, chronotype and insomnia) and myopia from FinnGen (n = 214,211) and UK Biobank (n = 460,536) were analyzed using linkage disequilibrium score regression (LD Score), univariable and multivariable mendelian randomization (MR) experiments and Causal Analysis Using Summary Effect (CAUSE) estimation. Results: LD Score regression detected candidate genetic correlation between sleep traits and myopia, such as sleep duration, chronotype (Genetic Correlation Z-score >10.00, h2 Conclusion: There may be a potential genetic correlation between sleep duration, chronotype and myopia. However, neither of sleep duration, chronotype or insomnia had causal effect on myopia.
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