Evidence map›Paper›PMID 39045054›Full record

ReviewFrontiers in pharmacology2024

Therapeutic targeting of voltage-gated sodium channel Na

Piyasuda Pukkanasut, Renata Jaskula-Sztul, Juan Carlos Gomora, Sadanandan E Velu

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Piyasuda PukkanasutDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL, United States.
Renata Jaskula-SztulDepartment of Surgery, The University of Alabama at Birmingham, Birmingham, AL, United States.
Juan Carlos GomoraDepartamento de Neuropatología Molecular, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Sadanandan E VeluDepartment of Chemistry, The University of Alabama at Birmingham, Birmingham, AL, United States.

Funding

Hydrogel encapsulated biofilm inhibitors for dental caries prevention and treatmentR21DE028349 · NIDCR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VELU, SADANANDAN E. · 2019 to 2020
$396k
Somatostatin receptor 2 (SSTR2) antibody-drug conjugate for pancreatic neuroendocrine tumor (PanNET) therapyR21CA226491 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JASKULA-SZTUL, RENATA, LIU, XIAOGUANG MARGARET · 2020 to 2021
$364k
NCI NIH HHS R21 CA226491NIDCR NIH HHS R21 DE028349
6 · The paper itself

Abstract

This review focuses on the expression and function of voltage-gated sodium channel subtype Na

Indexed as

cancercell invasioncell migrationcell viabilitymetastasisNav1.7therapeutic targetingvoltage-gated sodium channel

Identifiers

PMID39045054
PMCPMC11263763

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.