Evidence map›Paper›PMID 39044767›Full record

ArticleBiochemistry and biophysics reports2024

Investigation of the impact of copper nanoparticles coated with ocimum bassilicum at chemoradiotherapy of colon carcinoma.

Farshad Seyed Nejad, Mostafa Alizade-Harakiyan, Mehdi Haghi, Rokhsareh Ebrahimi, Mohammad Mahdi Zangeneh, Alireza Farajollahi, Roghayeh Fathi, Reza Mohammadi, Samira Samadi Miandoab, Mohammad Heydarnezhad Asl and 2 more

Abstract read
In one paragraph

Article in Biochemistry and biophysics reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Eco-friendly synthesis of copper nanoparticles by usingBiochemistry and biophysics reports · 2025
    Article
  6. Unveiling the Pharmacological Promise ofBioMed research international · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Farshad Seyed NejadMolecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mostafa Alizade-HarakiyanDepartment of Radiation Oncology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mehdi HaghiDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Rokhsareh EbrahimiMedicinal Chemistry Department, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Mahdi ZangenehDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Alireza FarajollahiDepartment of Radiation Oncology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Roghayeh FathiPolymer Research Laboratory, Department of Organic and Biochemistry, University of Tabriz, Tabriz, Iran.
Reza MohammadiPolymer Research Laboratory, Department of Organic and Biochemistry, University of Tabriz, Tabriz, Iran.
Samira Samadi MiandoabMolecular Medicine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Heydarnezhad AslDepartment of Animal Biology, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran.
Baharak DivbandDepartment of Inorganic Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, Iran.
Amin AhmadiResearch Center for Pharmaceutical Nanotechnology, Biomedicine Institute, Tabriz University of Medical Sciences, Tabriz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Colon carcinoma poses a significant health challenge globally, particularly in developed nations where sedentary lifestyles, poor dietary choices, and genetic factors play a crucial role in its prevalence. Chemotherapy, the primary treatment method, carries severe side effects that can jeopardize patients' lives. Herbal extracts such as Ocimum Basillicum extract have shown effectiveness against cancer cells. Additionally, nanoparticles can significantly enhance drug delivery efficacy in these scenarios. Aim: This article aims to investigate the impact of copper nanoparticles coated with Ocimum Bassilicum at chemoradiotherapy of Colon Carcinoma to hopefully create new treatment options with fewer side effects for patients. Methodology: CuO bio-NPs were produced by the addition of 15 mL of extract dropwise to 80 mL of a 5 mM Cu (OAc) Results: The results demonstrate a decrease in cell viability and the expression of Conclusions: After doing the clinical trial studies, the recent nanoparticles can be used for the treatment of Colorectal carcinoma.

Indexed as

Colon cancerCopper nanoparticlesOcimum basillicum extractRadioteraphy

Identifiers

PMID39044767
PMCPMC11263947

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.