Evidence map›Paper›PMID 39044608›Full record

ArticleMagnetic resonance in medicine2024

Acute nicotinamide riboside supplementation increases human cerebral NAD

Ravi Prakash Reddy Nanga, Corinde E Wiers, Mark A Elliott, Neil E Wilson, Fang Liu, Quy Cao, Sophie Swago, Paul S Jacobs, Ryan Armbruster, Damodara Reddy and 4 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. NADSpinal cord · 2026
    Review
  4. Redox Molecules in Aging and Neurodegenerative Disorders.International journal of molecular sciences · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ravi Prakash Reddy NangaCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3644-5656
Corinde E WiersDepartment of Psychiatry, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Mark A ElliottCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Neil E WilsonCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0002-7766-2929
Fang LiuDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Quy CaoDepartment of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Sophie SwagoDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-8334-4746
Paul S JacobsDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3566-4010
Ryan ArmbrusterDepartment of Bioengineering, School of Engineering and Applied Sciences, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Damodara ReddyCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Joseph A BaurDepartment of Physiology, Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Walter R WitscheyCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1669-2120
John A DetreDepartment of Neurology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ravinder ReddyCenter for Advanced Metabolic Imaging in Precision Medicine, Department of Radiology, Perelman School of Medicine at The University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
In vivo Mapping of Muscle Specific MetabolismR01AG071725 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2022 to 2026
$3.1M
Imaging of glutamatergic system changes in Alzheimer's disease in vivoR01AG063869 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2020 to 2024
$3.0M
Cardiac MR imaging of hemorrhagic reperfusion injury after myocardial infarctionR01HL137984 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WITSCHEY, WALTER R.T. · 2018 to 2022
$2.8M
Novel Imaging Biomarkers of Lipid and Ketone Metabolism in Alzheimer's DiseaseRF1AG087306 · NIA · UNIVERSITY OF PENNSYLVANIA · PI REDDY, RAVINDER · 2024 to 2024
$2.1M
Training in Structural, Physiologic and Functional MRIT32EB020087 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI JAMES C GEE, Chamith Sudesh Rajapakse · 2016 to 2026
$2.1M
NHLBI NIH HHS NIH HL137984NHLBI NIH HHS R01 HL137984NIA NIH HHS R01 AG063869NIA NIH HHS R01 AG071725NIA NIH HHS R01AG071725NIA NIH HHS RF1 AG087306NIBIB NIH HHS P41 EB029460NIBIB NIH HHS T32 EB020087
6 · The paper itself

Abstract

purposeThe purpose of this study was to determine the effect of acute nicotinamide riboside (NR) supplementation on cerebral nicotinamide adenine dinucleotide (NAD

methodsDF

resultsNR supplementation increased mean NAD

conclusionThese preliminary results confirm that acute NR supplementation increases cerebral NAD

Indexed as

BrainDietary SupplementsNADNiacinamidePyridinium CompoundsAdultFemaleHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleReproducibility of ResultsYoung AdultNADNiacinamidenicotinamide-beta-ribosidePyridinium CompoundsDF 1H MRSdownfield proton MRSNAD+nicotinamide adenine dinucleotidenicotinamide ribosideNR

Identifiers

PMID39044608
PMCPMC11436296

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.