ArticleThe journal of prevention of Alzheimer's disease2024
Global Burden of Dementia Death from 1990 to 2019, with Projections to 2050: An Analysis of 2019 Global Burden of Disease Study.
Article in The journal of prevention of Alzheimer's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Systematic review and meta-analysis of rural-urban disparities in Alzheimer's disease dementia prevalence.The journal of prevention of Alzheimer's disease · 2025Pooled it
- Natural Products in Alzheimer's Disease: A Systematic Review of Clinical Trials and Underlying Molecular Mechanisms.International journal of molecular sciences · 2025Pooled it
- Mortality of people with diagnosed dementia in Germany between 2016 and 2021.Alzheimer's research & therapy · 2026Article
- The growing burden of dementia in Asia: Comparative insights from Japan, China, and India.The journal of prevention of Alzheimer's disease · 2026Article
- Dynamic dementia risk before and after incident diabetes mellitus: a combined case-control and cohort study.BMC public health · 2026Article
- Review
- The Myokine Irisin Represents an Indirect Pathway Linking Exercise to Hippocampal Subfields Relevant to Alzheimer's Disease and Neurogenesis.Aging cell · 2026Article
- Cardiovascular-kidney-metabolic syndrome stages 0-3 and cognitive decline in Chinese adults: a longitudinal analysis from the China health and retirement longitudinal study.BMC cardiovascular disorders · 2026Article
- Resolving Heterogeneity in the Diagnosis of Alzheimer's Disease and its Progression Using Multimodal Data.Journal of molecular neuroscience : MN · 2026Article
- Trends and Determinants of Dementia-Related Mortality in Mexico, 2017-2023.Epidemiologia (Basel, Switzerland) · 2026Article
- Chemical and enantioselective GC-MS characterization ofFrontiers in pharmacology · 2026Article
- Population-based cohort study of modifiable risk factors for dementia and Alzheimer disease mortality in Spain.Communications health · 2026Article
- Association of remnant cholesterol with cognitive impairment: a cross-sectional study.Frontiers in human neuroscience · 2026Article
- The success-failure inversion in modern medicine.Frontiers in public health · 2026Article
- Marine-derived PUFAs and peptides for aging-related memory deficits: processing methods, pharmacokinetics, mechanistic insights, and clinical application.Frontiers in nutrition · 2026Review
- Decoding the Gut-Brain Axis in Alzheimer's Disease: Emerging Perspectives.CNS & neurological disorders drug targets · 2026Review
- Global burden, spatiotemporal disparities, and sex-specific trends of early- and late-onset Alzheimer's disease and other dementias: a comparative analysis and projections to 2035.BMC neurology · 2025Article
- High-sensitivity plasma proteomics reveals disease-specific signatures and predictive biomarkers of Alzheimer's disease phenotypes in a large mixed-dementia cohort.Molecular neurodegeneration · 2025Article
- Digital Dementia Education and Training for Informal Carers: A Scoping Review.Journal of clinical nursing · 2025Article
- Cardiovascular Disease as a Predictor of Dementia: A Cross-National Ecological Study of 204 Countries.Health science reports · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia is a growing global health challenge. Quantifying the current burden and predicting the future increases of dementia-related deaths are necessary to enhance effective policy decisions and health system planning.
methodsData on dementia mortality was derived from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 study. The 2020-2050 dementia-related deaths were forecasted using the Bayesian age-period-cohort model.
resultsGlobally, the number of dementia-related death increased from 0.56 million in 1990 to 1.62 million in 2019 and were estimated to increase to 4.91 million by the year 2050. Metabolic risk factors would become the most important modifiable risk factors affecting dementia death which account for 28.10% of dementia related death by the year 2050. For different Socio-demographic Index (SDI) regions, the low SDI region would have the highest age-standardized mortality rate (ASMR) (29.16 per 100,000) by 2050. Moreover, the number of dementia-related deaths under the age of 70 years was predicted to reach 0.18 million by 2050.
conclusionsDementia related death remains a global health problem, and health policies targeting metabolic risk factors may be an important way to alleviate this problem.
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