Evidence map›Paper›PMID 39044468›Full record

ArticleDrug delivery2024

Surface saturation of drug-loaded hollow manganese dioxide nanoparticles with human serum albumin for treating rheumatoid arthritis.

Ming Jia, Wei Ren, Minrui Wang, Yan Liu, Chenglong Wang, Zongquan Zhang, Maochang Xu, Nianhui Ding, Chunhong Li, Hong Yang

Abstract read
In one paragraph

Article in Drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Advances in the use of nanotechnology for treating gout.Nanomedicine (London, England) · 2025
    Review
  6. Review
  7. Recent advances in injectable hydrogels for osteoarthritis treatments.Frontiers in bioengineering and biotechnology · 2025
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ming JiaDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Wei RenNational Traditional Chinese Medicine Clinical Research Base and Drug Research Center of the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
Minrui WangSchool of Basic Medical Sciences, Southwest Medical University, Luzhou, China.
Yan LiuDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Chenglong WangDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Zongquan ZhangDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Maochang XuDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Nianhui DingSchool of Pharmacy, Southwest Medical University, Luzhou, China.
Chunhong LiDepartment of Pharmaceutical Sciences, School of Pharmacy, Southwest Medical University, Luzhou, China.
Hong YangSichuan Clinical Research Center for Birth Defects, Luzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease accompanied by energy depletion and accumulation of reactive oxygen species (ROS). Inorganic nanoparticles (NPs) offer great promise for the treatment of RA because they mostly have functions beyond being drug carriers. However, conventional nanomaterials become coated with a protein corona (PC) or lose their cargo prematurely

Indexed as

Arthritis, RheumatoidDrug CarriersManganese CompoundsMethotrexateNanoparticlesOxidesReactive Oxygen SpeciesSerum Albumin, HumanAnimalsAntirheumatic AgentsArthritis, ExperimentalCytokinesHumansMaleMiceRatsAntirheumatic AgentsCytokinesDrug CarriersManganese Compoundsmanganese dioxideMethotrexateOxidesReactive Oxygen SpeciesSerum Albumin, HumanalbuminmacrophagenanoparticleRheumatoid arthritissynoviocyte

Identifiers

PMID39044468
PMCPMC11271085

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.