ArticleEye (London, England)2024
Impacts of keratoconus on quality of life: a qualitative study.
Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Association Between Keratoconus and Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.Cornea · 2026Pooled it
- Keratoconus and quality of life: an updated comprehensive review.BMC ophthalmology · 2025Pooled it
- Depression among keratoconus patients: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Living Well with Keratoconus: Implications for Person-Centred Eye Care.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Association between attention deficit hyperactivity disorder and keratoconus.Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2026Article
- Prevalence and Associated Factors of Keratoconus in Latin America and the Caribbean: A Systematic Review and Meta-Analysis.Vision (Basel, Switzerland) · 2026Review
- Article
- One-Year Comparative Outcomes of Conventional Versus Accelerated Corneal Cross-Linking in Progressive Keratoconus.Medicina (Kaunas, Lithuania) · 2026Article
- Reduced Image Quality Impairs Monocular Blur-Driven Accommodation in Keratoconus.Investigative ophthalmology & visual science · 2026Article
- Article
- The Critical Role of Oxygen Supplementation in Epithelium-On Corneal Cross-Linking: A Narrative Review.Advances in therapy · 2026Review
- Evaluation of Factors Influencing Quality of Life in Keratoconus Patients Using the Keratoconus Outcomes Research Questionnaire (KORQ).Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Article
- Anterior Segment Eye Diseases and Quality of Life: An Updated Comprehensive Narrative Review.Journal of ophthalmic & vision research · 2026Review
- Contact Lenses and Vision-Related Quality of Life: Evidence and Clinical Insights.Clinical optometry · 2026Review
- Comparative Analysis of Corneal Densitometry Changes Following Standard Versus Accelerated Corneal Cross-Linking Protocol.Medicina (Kaunas, Lithuania) · 2025Article
- Corneal Topography - a Review of Available Investigation Methods and Impact in the Diagnosis and Follow-Up of Keratoconus.Maedica · 2025Article
- Assessment of Serum Cytokine Levels in Keratoconus Patients.Journal of clinical medicine · 2025Article
- Assessment of awareness of keratoconus and its relation to eye rubbing among Saudi Arabia population.Frontiers in ophthalmology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsTo identify the domains of quality of life (QoL) in people with keratoconus.
methodsSemi structured in-depth in person and telephone interviews were conducted with participants diagnosed with keratoconus and recruited from the Sydney Eye Hospital, Sydney, Australia. Thematic analysis of interview content was conducted using inductive and deductive processes. Data was collected until thematic saturation was obtained.
results33 patients with keratoconus with median age 37 (range 18 to 65) years and majority male (n = 25; 75.8%) were interviewed and a total of 2551 quotes coded. Thematic analysis resulted in 7 broad themes, Driving (199 references), Career (259 references), Symptoms (647 references), Enjoyment (149 references), Relationships (250 references), Financial (104 references) and Healthcare (881 references). Most references described a negative relationship between keratoconus and these 7 domains. The diverse QoL issues expressed included frustration with treatment effectiveness, fear of disease progression, inconvenience with contact lenses, forced career changes and job loss, cost of contact lenses, and feelings of isolation and discrimination. Themes and subthemes described a complex and varied relationship between keratoconus and QoL.
conclusionSevere quality of life impairment was experienced by keratoconus patients despite treatment. Keratoconus diminishes various aspects of individual's QoL. Therapies able to improve QoL are still needed for keratoconus.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.