Evidence map›Paper›PMID 39043686›Full record

ArticleNature communications2024

Engineering mouse cell fate controller by rational design.

Tao Huang, Dong Liu, Xiaomin Wang, Junqi Kuang, Manqi Wu, Beibei Wang, Zechuan Liang, Yixin Fan, Bo Chen, Zhaoyi Ma and 7 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Tao Huang *College of Life Sciences, Zhejiang University, Hangzhou, China.
Dong Liu *Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Xiaomin Wang *Laboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Junqi KuangLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Manqi WuLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Beibei WangLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Zechuan LiangCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Yixin FanCAS Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
Bo ChenLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Zhaoyi MaCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Yu FuLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Wenhui ZhangCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Jin MingLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Yue QinLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China.
Chengchen ZhaoLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China. zhaochengchen@westlake.edu.cn.ORCID 0000-0002-8454-6347
Bo WangLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China. wangbo@westlake.edu.cn.ORCID 0000-0003-1182-952X
Duanqing PeiLaboratory of Cell Fate Control, School of Life Sciences, Westlake University, Hangzhou, China. peiduanqing@westlake.edu.cn.ORCID 0000-0002-5222-014X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell fate is likely regulated by a common machinery, while components of this machine remain to be identified. Here we report the design and testing of engineered cell fate controller Nanog

Indexed as

Nanog Homeobox ProteinTranscription FactorsAnimalsCell DifferentiationCell EngineeringCellular ReprogrammingChromatinDNA HelicasesMiceNuclear ProteinsChromatinDNA HelicasesNanog Homeobox ProteinNanog protein, mouseNuclear ProteinsSmarca4 protein, mouseTranscription Factors

Identifiers

PMID39043686
PMCPMC11266670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.