Evidence map›Paper›PMID 39043390›Full record

ArticleEmerging infectious diseases2024

Phylogeographic Analysis of Mycobacterium kansasii Isolates from Patients with M. kansasii Lung Disease in Industrialized City, Taiwan.

Patrick George Tobias Cudahy, Po-Chen Liu, Joshua L Warren, Benjamin Sobkowiak, Chongguang Yang, Thomas R Ioerger, Chieh-Yin Wu, Po-Liang Lu, Jann-Yuan Wang, Hsiao-Han Chang and 3 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Patrick George Tobias Cudahy
Po-Chen Liu
Joshua L Warren
Benjamin Sobkowiak
Chongguang Yang
Thomas R Ioerger
Chieh-Yin Wu
Po-Liang Lu
Jann-Yuan Wang
Hsiao-Han Chang
Hung-Ling Huang
Ted Cohen
Hsien-Ho Lin

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Multidrug-resistant tuberculosis and HIV: Composition of Strains and biomarkers of treatment responseK01TW011194 · FIC · YALE UNIVERSITY · PI CUDAHY, PATRICK GEORGE TOBIAS · 2019 to 2023
$826k
FIC NIH HHS K01 TW011194NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

Little is known about environmental transmission of Mycobacterium kansasii. We retrospectively investigated potential environmental acquisition, primarily water sources, of M. kansasii among 216 patients with pulmonary disease from an industrial city in Taiwan during 2015-2017. We analyzed sputum mycobacterial cultures using whole-genome sequencing and used hierarchical Bayesian spatial network methods to evaluate risk factors for genetic relatedness of M. kansasii strains. The mean age of participants was 67 years; 24.1% had previously had tuberculosis. We found that persons from districts served by 2 water purification plants were at higher risk of being infected with genetically related M. kansasii isolates. The adjusted odds ratios were 1.81 (1.25-2.60) for the Weng Park plant and 1.39 (1.12-1.71) for the Fongshan plant. Those findings unveiled the association between water purification plants and M. kansasii pulmonary disease, highlighting the need for further environmental investigations to evaluate the risk for M. kansasii transmission.

Indexed as

Mycobacterium Infections, NontuberculousMycobacterium kansasiiPhylogeographyAgedAged, 80 and overFemaleHumansLung DiseasesMaleMiddle AgedPhylogenyRetrospective StudiesRisk FactorsTaiwanWhole Genome Sequencingbacteriaenvironmental exposuresgenetic relatednessMycobacterium kansasiiTaiwantransmissiontuberculosis and other mycobacteriawhole-genome sequencing

Identifiers

PMID39043390
PMCPMC11286038

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.