Evidence map›Paper›PMID 39043245›Full record

ArticleProceedings. Biological sciences2024

Reorganization of circadian activity and the pacemaker circuit under novel light regimes.

Pragya Niraj Sharma, Vasu Sheeba

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pragya Niraj SharmaNeuroscience Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.ORCID 0000-0003-4492-2720
Vasu SheebaNeuroscience Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.ORCID 0000-0003-2924-7130

Funding

Jawaharlal Nehru Centre for Advanced Scientific Research
6 · The paper itself

Abstract

Many environmental features are cyclic, with predictable changes across the day, seasons and latitudes. Additionally, anthropogenic, artificial-light-induced changes in photoperiod or shiftwork-driven novel light/dark cycles also occur. Endogenous timekeepers or circadian clocks help organisms cope with such changes. The remarkable plasticity of clocks is evident in the waveforms of behavioural and molecular rhythms they govern. Despite detailed mechanistic insights into the functioning of the circadian clock, practical means to manipulate activity waveform are lacking. Previous studies using a nocturnal rodent model showed that novel light regimes caused locomotor activity to bifurcate such that mice showed two bouts of activity restricted to the dimly lit phases. Here, we explore the generalizability of these findings and leverage the genetic toolkit of

Indexed as

Circadian RhythmDrosophila melanogasterAnimalsCircadian ClocksCryptochromesLightMalePhotoperiodCryptochromescircadian circuitcryptochromedim lightDrosophilalocomotor activity bifurcationwaveform plasticity

Identifiers

PMID39043245
PMCPMC11265910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.