Evidence map›Paper›PMID 39043185›Full record

ArticleImmunity2024

Dynamic landscapes and protective immunity coordinated by influenza-specific lung-resident memory CD8

Stephanie van de Wall, Scott M Anthony, Lisa S Hancox, Lecia L Pewe, Ryan A Langlois, Dietmar Zehn, Vladimir P Badovinac, John T Harty

Abstract read
In one paragraph

Article in Immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Monocytes in pneumonia: Functional plasticity and innate memory (Review).International journal of molecular medicine · 2026
    Review
  2. Good neighbors make lasting memory.Nature immunology · 2026
    Article
  3. The ageing immune system and its battle with viruses.The Journal of general virology · 2026
    Review
  4. Renaissance of antiviral CD8Nature reviews. Immunology · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Stephanie van de WallDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Scott M AnthonyDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Lisa S HancoxDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Lecia L PeweDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
Ryan A LangloisUniversity of Minnesota, Department of Microbiology and Immunology and the Center for Immunology, Minneapolis, MN, USA.
Dietmar ZehnTUM Center for Infection Prevention (ZIP) and Division of Animal Physiology and Immunology, TUM School of Life Sciences, Technical University of Munich, Freising, Germany.
Vladimir P BadovinacDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
John T HartyDepartment of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Interdisciplinary Graduate Program in Immunology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA. Electronic address: john-harty@uiowa.edu.

Funding

Viral VectorP30CA086862 · NCI · UNIVERSITY OF IOWA · PI Christopher K Laubenthal · 2000 to 2026
$70.0M
Regulation of primary and secondary CD4 and CD8 T cell memoryR37AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2008 to 2017
$4.7M
Memory CD8 T cell localization and protection from influenzaR01AI114543 · NIAID · UNIVERSITY OF IOWA · PI BADOVINAC, VLADIMIR P, HARTY, JOHN T · 2015 to 2024
$4.4M
T resident memory in the lungR01AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 1998 to 2023
$4.4M
Immunity to Liver-stage malariaR01AI167847 · NIAID · UNIVERSITY OF IOWA · PI John T Harty · 2022 to 2026
$3.0M
Mechanisms and consequences of epithelial cell survival from influenza virus infection.R01AI132962 · NIAID · UNIVERSITY OF MINNESOTA · PI LANGLOIS, RYAN · 2017 to 2021
$2.3M
Regulating Pathogen-induced Protective and Pathogenic CD8 T cells in the CNSR21AI178159 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T · 2023 to 2024
$414k
CD8+ T Cell effector mechanisms against L. monocytogenesR21AI042767 · NIAID · UNIVERSITY OF IOWA · PI HARTY, JOHN T. · 2002 to 2002
$331k
NIAID NIH HHS R01 AI042767NIAID NIH HHS R01 AI114543NIAID NIH HHS R01 AI132962NIAID NIH HHS R01 AI167847NIAID NIH HHS R21 AI042767NIAID NIH HHS R21 AI178159NIAID NIH HHS R37 AI042767
6 · The paper itself

Abstract

Lung-tissue-resident memory (T

Indexed as

Antigens, CDCD8-Positive T-LymphocytesImmunologic MemoryInfluenza A virusIntegrin alpha ChainsLungMemory T CellsOrthomyxoviridae InfectionsAnimalsInterferon-gammaIntravital MicroscopyMiceMice, Inbred C57BLMonocytesalpha E integrinsAntigens, CDIntegrin alpha ChainsInterferon-gammainfluenza virusintravital imaginglung T resident memory

Identifiers

PMID39043185
PMCPMC12001675

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.