Evidence map›Paper›PMID 39043172›Full record

ArticleThe American journal of tropical medicine and hygiene2024

Recurring Transient Tooth Pain as Newly Described Symptom of Migratory Loiasis: A Mixed-Methods Study in Rural Gabon.

Teite Rebecca Hildebrandt, Helmut Ramharter, Anita Lumeka Kabwende, Lilian Endamne, Saskia D Davi, Ayôla Akim Adegnika, Ghyslain Mombo-Ngoma, Selidji T Agnandji, Johannes Mischlinger, Rella Manego Zoleko and 1 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Oro-facial filariasis-A systematic review of the literature.PLoS neglected tropical diseases · 2024
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Teite Rebecca HildebrandtCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Helmut RamharterCenter for Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine and I. Department of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Anita Lumeka KabwendeCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Lilian EndamneCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Saskia D DaviCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Ayôla Akim AdegnikaCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Ghyslain Mombo-NgomaCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Selidji T AgnandjiCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Johannes MischlingerCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Rella Manego ZolekoCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.
Michael RamharterCentre de Recherches Médicales de Lambaréné, Lambarene, Gabon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Loiasis, a filarial pathogen exclusively endemic in central and western Africa, causes a wide spectrum of symptoms. Understanding the breadth of its clinical manifestations is of importance for adequate patient care and to understand its disease burden. Recurring transient pain in the oral cavity was reported as a self-perceived symptom of loiasis in in-depth interviews of patients in a high transmission region in Gabon. Pain was described as stabbing in character and transient for a few days in its temporal course. A quantitative epidemiological survey indicated that transient tooth pain was experienced by 22% of patients infected with Loa loa. Among those individuals, it was exclusively reported by patients suffering from migratory loiasis (24%). Similar findings have been previously described for other filarial pathogens, indicating that transient swellings of the periodontium and the soft tissue of the oral cavity may explain this symptom reported by patients with migratory loiasis.

Indexed as

LoiasisToothacheAdolescentAdultAnimalsFemaleGabonHumansLoaMaleMiddle AgedRecurrenceRural PopulationYoung Adult

Identifiers

PMID39043172
PMCPMC11448542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.