Evidence map›Paper›PMID 39043170›Full record

ArticleThe American journal of tropical medicine and hygiene2024

First Detection of Antibodies Specific to Crimean-Congo Hemorrhagic Fever Virus in Rural Populations of Gabon.

Linda Bohou Kombila, Solène Lerolle, Illich Manfred Mombo, Neil-Michel Longo-Pendy, Danielle Koumba Mavoungou, Gaël Darren Maganga, Francois-Loïc Cosset, Jessica Vanhomwegen, Christina Deschermeier, Eric Maurice Leroy and 3 more

Abstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Linda Bohou KombilaDépartement de Virologie, Unité Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Solène LerolleCentre International de Recherche en Infectiologie, Université de Lyon, Université Claude Bernard Lyon 1, l'Institut National de la Santé et de la Recherche Médicale, U1111, Centre National de la Recherche Scientifique, UMR5308 École Normale Supérieure de Lyon, Lyon, France.
Illich Manfred MomboDépartement de Virologie, Unité Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Neil-Michel Longo-PendyUnité de Recherche en Ecologie de la Santé, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Danielle Koumba MavoungouDépartement de Virologie, Unité Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Gaël Darren MagangaDépartement de Virologie, Unité Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Francois-Loïc CossetCentre International de Recherche en Infectiologie, Université de Lyon, Université Claude Bernard Lyon 1, l'Institut National de la Santé et de la Recherche Médicale, U1111, Centre National de la Recherche Scientifique, UMR5308 École Normale Supérieure de Lyon, Lyon, France.
Jessica VanhomwegenCellule d'Intervention Biologique d'Urgence, Institut Pasteur de Paris, Paris, France.
Christina DeschermeierPanadea Diagnostics GmbH, Hamburg, Germany.
Eric Maurice LeroyMaladies Infectieuses et Vecteurs, Ecologie, Génétique, Evolution et Contrôle, Université Montpellier, Institut de Recherche pour la Développement, Centre National de la Recherche Scientifique, Montpellier, France.
Vincent LegrosCentre International de Recherche en Infectiologie, Université de Lyon, Université Claude Bernard Lyon 1, l'Institut National de la Santé et de la Recherche Médicale, U1111, Centre National de la Recherche Scientifique, UMR5308 École Normale Supérieure de Lyon, Lyon, France.
Nadine N'dilimabakaDépartement de Virologie, Unité Emergence des Maladies Virales, Centre Interdisciplinaire de Recherches Médicales de Franceville, Franceville, Gabon.
Pierre BecquartMaladies Infectieuses et Vecteurs, Ecologie, Génétique, Evolution et Contrôle, Université Montpellier, Institut de Recherche pour la Développement, Centre National de la Recherche Scientifique, Montpellier, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease with a mortality rate reaching up to 40% in humans. Currently, CCHF affects three continents: Asia, Europe, and Africa. An increase in confirmed cases in Africa has been observed since 2000. In Central Africa, several countries have reported the circulation of CCHV virus (CCHFV). However, in Gabon, there is a lack of recent data on the circulation of the virus in the Gabonese population. To provide an overview of the epidemiological situation in Gabon, we tested 3,081 human serum samples collected between 2005 and 2008 in villages throughout the country for anti-CCHFV antibodies. Using a double-antigen ELISA kit, our study found 15/3,081 samples positive for CCHFV. These positive samples were also tested using the Blackbox CCHFV IgG kit and the Luminex technique. These analyses confirmed seven and four positives for the Blackbox CCHFV IgG kit and the Luminex technique, respectively. This study suggests low circulation of CCHFV in the rural human population of Gabon. Competent authorities must survey CCHFV to identify and prevent clinical cases in the human population.

Indexed as

Antibodies, ViralEnzyme-Linked Immunosorbent AssayHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoRural PopulationAdolescentAdultAgedChildChild, PreschoolFemaleGabonHumansImmunoglobulin GMaleMiddle AgedAntibodies, ViralImmunoglobulin G

Identifiers

PMID39043170
PMCPMC11448543

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.