Evidence map›Paper›PMID 39043021›Full record

ArticleESMO open2024

Patients with cancer who will be cured and projections of complete prevalence in Italy from 2018 to 2030.

S Guzzinati, F Toffolutti, S Francisci, A De Paoli, F Giudici, R De Angelis, E Demuru, L Botta, A Tavilla, G Gatta and 36 more

Abstract read
In one paragraph

Article in ESMO open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Cancer incidence and mortality trends from 2007 to 2021 in Milan.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

46 authors.

S GuzzinatiVeneto Tumour Registry, Epidemiological Department, Azienda Zero, Padova. Electronic address: stefano.guzzinati@azero.veneto.it.
F ToffoluttiCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
S FrancisciNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome.
A De PaoliVeneto Tumour Registry, Epidemiological Department, Azienda Zero, Padova.
F GiudiciCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
R De AngelisDepartment of Oncology and Molecular Medicine, National Institute of Health, Rome.
E DemuruDepartment of Oncology and Molecular Medicine, National Institute of Health, Rome.
L BottaEvaluative Epidemiology Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan.
A TavillaNational Centre for Disease Prevention and Health Promotion, National Institute of Health, Rome.
G GattaEvaluative Epidemiology Unit, Department of Epidemiology and Data Science, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan.
R CapocacciaEpidemiologia & Prevenzione Editorial Board, Milan.
M ZorziVeneto Tumour Registry, Epidemiological Department, Azienda Zero, Padova.
A CaldarellaTuscany Cancer Registry, Clinical Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network (ISPRO), Florence.
E BidoliCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
F FalciniEmilia-Romagna Cancer Registry, Romagna Unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Forlì.
R BruniCoordination Centre of the Cancer Registry of Puglia - Strategic Regional Agency for Health and Social Care (AReSS), Bari.
E MigliorePiedmont Cancer Registry, CPO Piemonte and University of Turin, Turin.
A PuppoLiguria Cancer Registry, IRCCS Ospedale Policlinico San Martino, Genova.
M FerranteRegistro Tumori Integrato di Catania-Messina-Enna, UOC Igiene Ospedaliera, Azienda Ospedaliero-Universitaria Policlinico G. Rodolico-San Marco, Catania.
C GasparottiATS Brescia Cancer Registry, Struttura Semplice di Epidemiologia, Brescia.
M L GambinoRegistro Tumori ATS Insubria (Provincia di Como e Varese) Responsabile S.S. Epidemiologia Registri Specializzati e Reti di Patologia, Varese.
G CarrozziEmilia-Romagna Cancer Registry, Modena Unit, Public Health Department, Local Health Authority, Modena.
F BianconiUmbria Cancer Registry, PuntoZero Scarl, Perugia.
A MusolinoEmilia-Romagna Cancer Registry, Parma Unit, Medical Oncology Unit, University Hospital of Parma, Parma.
R CavalloRegistro Tumori ASL Salerno-Dipartimento di Prevenzione, Salerno.
W MazzuccoClinical epidemiology and Cancer Registry Unit, Azienda Ospedaliera Universitaria Policlinico (AOUP) di Palermo, Palermo.
M FuscoUOSD Registro Tumori ASL Napoli 3 Sud, Napoli.
P BallotariSC Osservatorio Epidemiologico, ATS Val Padana, Mantova.
G SampietroBergamo Cancer Registry, Epidemiological Service, Agenzia di Tutela della Salute, Bergamo.
S FerrettiEmilia-Romagna Cancer Registry, Ferrara Unit, Local Health Authority, Ferrara; University of Ferrara, Ferrara.
L MangoneEmilia-Romagna Cancer Registry, Reggio Emilia Unit, Epidemiology Unit, Azienda Unità Sanitaria Locale - IRCCS di Reggio Emilia, Reggio Emilia.
W MantovaniTrento Province Cancer Registry, Clinical and Evaluative Epidemiology Unit, Local Health Authority, Trento.
M MianInnovation, Research and Teaching Service (SABES-ASDAA), Teaching Hospital of the Paracelsus Medical Private University (PMU); College of Health Care-Professions Claudiana, Bolzano-Bozen.
G CasconeAzienda Sanitaria Provinciale Ragusa - UOSD Registro Tumori, Ragusa.
F ManzoniCancer Registry of the Province of Pavia - Epidemiology Unit - Health Protection Agency of Pavia, Pavia.
R GalassoUnit of Regional Cancer Registry, Clinical Epidemiology and Biostatistics, IRCCS CROB, Rionero in Vulture (PZ).
D PirasNord Sardegna Cancer Registry, ASL Sassari, Sassari.
M T PesceMonitoraggio rischio ambientale e Registro Tumori ASL Caserta, Caserta.
F BellaSiracusa Cancer Registry, Provincial Health Authority of Siracusa, Siracusa.
P SeghiniEmilia-Romagna Cancer Registry, Piacenza Unit, Unit of Epidemiology AUSL Piacenza, Piacenza.
A C FanettiAgenzia di Tutela della Salute della Montagna Cancer Registry, Sondrio.
P PinnaNuoro Cancer Registry, ASL Nuoro, Nuoro, Italy.
D SerrainoCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano.
S RossiDepartment of Oncology and Molecular Medicine, National Institute of Health, Rome.
L Dal MasoCancer Epidemiology Unit, Centro di Riferimento Oncologico di Aviano (CRO), IRCCS, Aviano. Electronic address: dalmaso@cro.it.
AIRTUM Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number and projections of cancer survivors are necessary to meet the healthcare needs of patients, while data on cure prevalence, that is, the percentage of patients who will not die of cancer by time since diagnosis, are lacking. MATERIALS AND

methodsData from Italian cancer registries (duration of registration ranged from 9 to 40 years, with a median of 22 years) covering 47% of the population were used to calculate the limited-duration prevalence, the complete prevalence in 2018, projections to 2030, and cure prevalence, by cancer type, sex, age, and time since diagnosis.

resultsA total of 3 347 809 people were alive in Italy in 2018 after a cancer diagnosis, corresponding to 5.6% of the resident population. They will increase by 1.5% per year to 4 012 376 in 2030, corresponding to 6.9% of the resident population, 7.6% of women and ∼22% after age 75 years. In 2030, more than one-half of all prevalent cases (2 million) will have been diagnosed by ≥10 years. Those with breast (1.05 million), prostate (0.56 million), or colorectal cancers (0.47 million) will be 52% of all prevalent patients. Cure prevalence was 86% for all patients alive in 2018 (87% for patients with breast cancer and 99% for patients with thyroid or testicular cancer), increasing with time since diagnosis to 93% for patients alive after 5 years and 96% after 10 years. Among patients who survived at least 5 years, the excess risk of death (1 - cure prevalence) was <5% for patients with most cancer types except for those with cancers of the breast (8.3%), lung (11.1%), kidney (13.2%), and bladder (15.5%).

conclusionsStudy findings encourage the implementation of evidence-based policies aimed at improving long-term clinical follow-up and rehabilitation of people living after cancer diagnosis throughout the course of the disease. Updated estimates of complete prevalence are important to enhance data-driven cancer control planning.

Indexed as

NeoplasmsAdolescentAdultAgedAged, 80 and overCancer SurvivorsChildChild, PreschoolFemaleForecastingHumansInfantInfant, NewbornItalyMaleMiddle Agedcancer curecancer survivorscomplete prevalenceItalyprojections

Identifiers

PMID39043021
PMCPMC11321301

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