ArticleProceedings of the National Academy of Sciences of the United States of America2024
Directed evolution of material-producing microorganisms.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- CelluBase: a comprehensive genomic platform for advancing cellulose-producing bacteria.Microbial genomics · 2026Article
- Structural adaptations for enhanced translation kinetics in evolved ribosomes.Nucleic acids research · 2026Article
- Cell-in-Bead-in-Droplet Platform for pH-Based Microfluidic Screening of Ureolytic Bacteria.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Hydrogel platforms for engineered live biotherapeutics: materials, microbial integration and clinical potential.RSC pharmaceutics · 2026Review
- Structural adaptations for enhanced translation kinetics in evolved ribosomes.bioRxiv : the preprint server for biology · 2026Article
- Fit for purpose: evaluation and evolution of agricultural bioinoculants across production landscapes.ISME communications · 2026Review
- Bacterial Cellulose for Sustainable Food Packaging: Production Pathways, Structural Design, and Functional Modification Strategies.Polymers · 2025Review
- Self-organization of cellulose-producing microbial communities during biofilm spreading.Soft matter · 2025Article
- Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Chemical Modification Methods for Inulin- and Agavin-Type Fructans: Synthesis, Characterization, and Biofunctional Activity: A Review.Molecules (Basel, Switzerland) · 2025Review
- Anisotropic Growth of Filamentous Fungi in Wood Hydrogel Composites Increases Mechanical Properties.ACS applied bio materials · 2025Article
- Bacterial cellulose: Enhancing productivity and material properties through repeated harvest.Biofilm · 2025Article
- Solving Challenges in Microalgae-Based Living Materials.ACS synthetic biology · 2025Article
- Three-Dimensional Hierarchical Cellulose Structures Based on Microbial Synthesis and Advanced Biofabrication.Chem & bio engineering · 2024Review
- Evolving materials.Nature materials · 2024Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Nature is home to a variety of microorganisms that create materials under environmentally friendly conditions. While this offers an attractive approach for sustainable manufacturing, the production of materials by native microorganisms is usually slow and synthetic biology tools to engineer faster microorganisms are only available when prior knowledge of genotype-phenotype links is available. Here, we utilize a high-throughput directed evolution platform to enhance the fitness of whole microorganisms under selection pressure and identify genetic pathways to enhance the material production capabilities of native species. Using
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.