Evidence map›Paper›PMID 39042226›Full record

ArticleMolecular biology reports2024

Employing novel biocompatible composite scaffolds with bioglass 58S and poly L-lactic acid for effective bone defect treatment.

Erfan Motalebzadeh, Saideh Hemati, Mohanna Akbarin Mayvani, Marzieh Ghollasi

Abstract read
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Article in Molecular biology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Erfan MotalebzadehDepartment of Biology, Basic Science Faculty, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Saideh HematiDepartment of Cellular and Molecular Biology, Faculty of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Mohanna Akbarin MayvaniDepartment of Cellular and Molecular Biology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Marzieh GhollasiDepartment of Cell and Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran. ghollasi@khu.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBioglass materials have gained significant attention in the field of tissue engineering due to their osteoinductive and biocompatible properties that promote bone cell differentiation. In this study, a novel composite scaffold was developed using a sol-gel technique to combine bioglass (BG) 58 S with a poly L-lactic acid (PLLA). METHODS AND

resultsThe physiochemical properties, morphology, and osteoinductive potential of the scaffolds were investigated by X-ray diffraction analysis, scanning electron microscopy, and Fourier-transform infrared spectroscopy. The results showed that the SiO

conclusionsThese in vitro studies suggest that composite scaffolds incorporating hBMSCs are a promising substitute material to be implemented in bone tissue engineering. The PLLA/BG scaffolds promote osteogenesis and support the differentiation of bone cells, such as osteoblasts, due to their osteoinductive properties.

Indexed as

Biocompatible MaterialsCell DifferentiationCeramicsOsteogenesisPolyestersTissue EngineeringTissue ScaffoldsAlkaline PhosphataseBone and BonesBone RegenerationHumansMesenchymal Stem CellsMicroscopy, Electron, ScanningOsteoblastsSpectroscopy, Fourier Transform InfraredX-Ray DiffractionAlkaline PhosphataseBiocompatible MaterialsBioglassPolyesterspoly(lactide)Bioglass 58SBone marrow mesenchymal stem cellsOsteogenic differentiation

Identifiers

PMID39042226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.