Evidence map›Paper›PMID 39041706›Full record

ArticleThe Journal of infectious diseases2024

Prevalence of Oral Human Papillomavirus Infection Among Urban Gay, Bisexual, and Other Men Who Have Sex With Men in Canada, 2017-2019.

Jenna Alessandrini, Joseph Cox, Alexandra de Pokomandy, Trevor A Hart, Daniel Grace, Troy Grennan, David Moore, Gilles Lambert, Catharine Chambers, Shelley L Deeks and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jenna AlessandriniDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Joseph CoxDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montréal, Quebec, Canada.
Alexandra de PokomandyResearch Institute of the McGill University Health Centre, Montréal, Quebec, Canada.
Trevor A HartDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Daniel GraceDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Troy GrennanBritish Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
David MooreBritish Columbia Centre for Excellence in HIV/AIDS, Vancouver, British Columbia, Canada.
Gilles LambertDirection de Santé Publique de Montréal, Montréal, Quebec, Canada.
Catharine ChambersDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Shelley L DeeksDepartment of Health and Wellness, Nova Scotia, Halifax, Nova Scotia, Canada.
Ramandip GrewalDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Nathan J LachowskySchool of Public Health and Social Policy, University of Victoria, Victoria, British Columbia, Canada.
Chantal SauvageauImmunization, Institut National de Santé Publique du Québec, Quebec, Quebec, Canada.ORCID 0000-0002-4300-1658
Darrell H S TanMAP Centre for Urban Health Solutions, Unity Health Toronto, Toronto, Ontario, Canada.
François CoutléeDepartment of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montréal, Quebec, Canada.
Ann N BurchellMAP Centre for Urban Health Solutions, Unity Health Toronto, Toronto, Ontario, Canada.ORCID 0000-0003-2822-2169
Engage-HPV Team

Funding

Canada Research ChairCanadian Association for HIV/AIDS Research EngageCanadian Immunization Research NetworkCIHR TE2-138299CIHR Canadian HIV/AIDS Trials Network CTN300Fonds de Recherche du Québec-SantéMichael Smith Foundation for Health Research 16863Michael Smith Health Research BCOntario HIV Treatment Network 1051Public Health Agency of Canada 4500345082Toronto Metropolitan UniversityUniversity of Toronto
6 · The paper itself

Abstract

backgroundOral human papillomavirus (HPV) infections are a leading cause of oropharyngeal cancers. In 2015 and 2016, HPV vaccines became publicly funded for gay, bisexual, and other men who have sex with men (GBM) under 27 years of age in most Canadian provinces.

methodsBetween 2017 and 2019, sexually active GBM in Montreal, Toronto, and Vancouver were recruited through respondent-driven sampling. Participants aged 16-30 years were invited to self-collect oral rinse specimens for HPV testing. We estimated HPV prevalence in the oral tract overall and compared these by vaccination status.

resultsAmong the 838 GBM with a valid oral specimen, 36.9% reported receiving ≥1 dose of HPV vaccine. Overall, oral HPV prevalence was 2.6% (95% confidence interval [CI], 1.5%-3.7%) for at least 1 HPV type and 1.2% (95% CI, .5%-1.9%) for any high-risk type. We detected quadrivalent (HPV 6/11/16/18) vaccine-preventable types in 0.3% (95% CI, .0%-1.0%) of vaccinated individuals and 1.1% (95% CI, .1%-2.0%) of unvaccinated individuals.

conclusionsOral HPV prevalence was low in a population of young urban GBM in Canada, of whom 37% were vaccinated. Findings serve as a benchmark for monitoring of vaccination impacts on oral HPV infection within this priority population.

Indexed as

Homosexuality, MalePapillomavirus InfectionsPapillomavirus VaccinesSexual and Gender MinoritiesAdolescentAdultCanadaHumansMalePapillomaviridaePrevalenceUrban PopulationVaccinationYoung AdultPapillomavirus Vaccinesgay, bisexual, and other men who have sex with menoral human papillomavirusvaccine effectiveness

Identifiers

PMID39041706
PMCPMC11566233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.