Evidence map›Paper›PMID 39040901›Full record

ArticleFrontiers in microbiology2024

Changes in the ocular surface microbiome of patients with coronavirus disease 2019 (COVID-19).

Jia Lin, Jingrao Wang, Jiaoyang Feng, Rui Zhu, Yu Guo, Yueyan Dong, Hong Zhang, Xin Jin

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia LinDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jingrao WangDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Jiaoyang FengDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Rui ZhuDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yu GuoDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yueyan DongDepartment of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Hong Zhang *Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Xin Jin *Department of Ophthalmology, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To elucidate the reasons behind the increased incidence of ocular disease in patients with coronavirus disease 2019 (COVID-19), this study delved deeper into the specific effects of COVID-19 on patients' ocular surface microbiome (OSM) and investigated its relationship with the increased incidence of ocular disease. Methods: In this study, conjunctival sac swabs were collected from 43 participants for 16S rRNA amplicon sequencing. The participants were categorized into three groups based on their COVID-19 status: the control group (C group) consisted of 15 participants who showed no evidence of COVID-19, the experimental group (E group) included 15 participants who tested positive for COVID-19, and the COVID-19 recovery period group (R group) comprised 13 participants. Results: In the comparison of alpha diversity, group E had a higher Shannon, Chao1 and Goods coverage index. When comparing beta diversity, groups E and R were more similar to each other. At the phylum level, although the OSM of the three groups was dominated by Conclusion: This study provides additional evidence supporting the association between the OSM and COVID-19, which contributes to our understanding of the potential mechanisms underlying ocular symptoms and complications associated with COVID-19 in the future.

Indexed as

16S rRNA amplicon sequencingCOVID-19COVID-19 recovery periodocular surfaceocular surface microbiome

Identifiers

PMID39040901
PMCPMC11262004

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