Evidence map›Paper›PMID 39040537›Full record

ArticleFrontiers in neurology2024

Risk factors for postoperative late deterioration in patients with spinal dural arteriovenous fistulas.

Yuanhong Ge, Qingjia Lai, Wei Guo, Xuejun Xu

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Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yuanhong Ge *Department of Neurosurgery, Chengdu Second People's Hospital, Chengdu, China.
Qingjia Lai *Department of Rehabilitation, Care Alliance Rehabilitation Hospital of Chengdu, Chengdu, China.
Wei GuoDepartment of Neurosurgery, Tangdu Hospital, Air Force Military Medical University, Xi'an, China.
Xuejun XuDepartment of Neurosurgery, Chengdu Second People's Hospital, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Approximately 86% of patients with spinal dural arteriovenous fistulas (SDVAFs) exhibit clinical improvement after surgery. However, 12%-55.8% of these patients experience late deterioration (LD) after an initial period of improvement. The risk factors for LD remain unclear. The aim of this study was to explore the risk factors for LD in SDVAF patients. Methods: The clinical data of patients who were admitted to two tertiary hospitals between June 2014 and May 2022 were reviewed. Patients were divided into two groups: the LD group and the no LD group. The severity of neurological dysfunction (NDF) was evaluated using the Modified Aminoff and Logue Scale. Univariable and multivariable Cox regression analyses were performed. Results: A total of 105 eligible patients were enrolled, with a mean age of 57.55 ± 9.42 years. The LD group comprised 37 individuals, while the no LD group consisted of 68 individuals. According to the univariable analysis, preoperative NDF severity and treatment strategy were associated with the risk of LD. According to the multivariable analysis, patients who underwent microsurgery (MS) had a lower risk of LD than did those who underwent endovascular treatment (EVT; HR 0.197, 95% CI 0.085-0.457), and patients with severe NDF had a higher risk of LD than did those with mild NDF (HR 3.604, 95% CI 1.226-10.588), whereas the risk of LD in patients with moderate NDF was similar to that of patients with mild NDF (HR 1.352, 95% CI 0.519-3.524). Conclusion: EVT and severe preoperative NDF are independent risk factors for LD.

Indexed as

late deterioration (LD)neurological dysfunction (NDF)risk factorsspinal dural arteriovenous fistula (SDAVF)treatment

Identifiers

PMID39040537
PMCPMC11260714

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