ArticleAlzheimer's & dementia (Amsterdam, Netherlands)
Lifestyle and psychosocial associations with cognition at the cusp of midlife using twins and siblings.
Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Cognitive dispersion in established adulthood: etiology and implications for cognitive aging.Innovation in aging · 2026Article
- How's Your Memory? Convergence of Objective and Subjective Memory Performance Using Ambulatory Assessment in Middle Age.Innovation in aging · 2025Article
- From controllers to cognition: the importance of selection factors on video game and gameplay mechanic-derived cognitive differences.Behavioral and brain functions : BBF · 2024Article
- A Genetically Informed Study of Digital screen time, Video game play, and Impulsivity in Established Adulthood.Computers in human behavior · 2024Article
- Lifestyle and psychosocial associations with cognition at the cusp of midlife using twins and siblings.Alzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
6 authors.
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Abstract
introductionThis study investigates the relationship between cognitive functioning and 59 modifiable and intrinsic factors at the cusp of midlife.
methodsWe analyzed data from 1221 participants in the Colorado Adoption/Twin Study of Lifespan behavioral development and cognitive aging (CATSLife; M
resultsEight robust factors were identified, including education attainment, cognitive complexity, purpose-in-life, and smoking status. Twins reporting higher levels of cognitive complexity and purpose-in-life showed better cognitive performance than their cotwin, while smoking was negatively associated. Using meta-analytically derived effect size threshold, we additionally identified that twins experiencing more financial difficulty tend to perform less well compared with their cotwin. DISCUSSION: The findings highlight the early midlife link between cognitive functioning and lifestyle/psychological factors, beyond prior cognitive performance, brain status, genetic and familial confounders. Our results further highlight the potential of established adulthood as a crucial window for dementia prevention interventions targeting lifestyle and psychosocial factors. Highlights: Cog complexity(+), purpose-in-life(+) were associated with cognition in early midlife.Smoking(-) was also associated with cognition in early midlife.Results were consistent controlling for genetic and environmental confounds.Association between EA and cognition might be mostly genetic and familial confounded.
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