ArticlemedRxiv : the preprint server for health sciences2024
Laminar multi-contrast fMRI at 7T allows differentiation of neuronal excitation and inhibition underlying positive and negative BOLD responses.
Xingfeng Shao, Fanhua Guo, JungHwan Kim, David Ress, Chenyang Zhao, Qinyang Shou, Kay Jann, Danny Jj Wang
Abstract readPreprint
In one paragraphArticle in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
8 authors.
Xingfeng ShaoLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.ORCID 0000-0002-4130-6204 Fanhua GuoLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
JungHwan KimVivian L. Smith Department of Neurosurgery, McGovern Medical School, University of Texas Health Science Center at Houston.
David RessDepartment of Neuroscience, Baylor College of Medicine.
Chenyang ZhaoLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
Qinyang ShouLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
Kay JannLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
Danny Jj WangLaboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California.
Funding
Validation of Imaging and Blood-based Small Vessel VCID Biomarkers in Multiethnic PopulationUF1NS100614 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KASHANI, AMIR H, RINGMAN, JOHN M · 2021 to 2021
$2.6MImaging Cerebral Small Vessels in Vascular Cognitive Impairment and Dementia (VCID)RF1AG084072 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JIANG, XUEJUAN, SHI, YONGGANG · 2023 to 2023
$2.5MLaminar Perfusion ImagingR01EB032169 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Danny JJ WANG · 2021 to 2026
$2.5MMultiband ASL for Neurodevelopment StudyR01EB028297 · NIBIB · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, DANNY JJ · 2019 to 2023
$2.2MCharacterization of neurovascular and neurometabolic coupling of the negative BOLD response in humanR01NS121040 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JungHwan Kim · 2022 to 2026
$1.9MBBB Permeability Imaging in CADASILR01NS114382 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, DANNY JJ · 2020 to 2024
$1.2MNOVA PTX Coil for Ultrahigh Field ImagingS10OD025312 · OD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI WANG, DANNY JJ · 2018 to 2018
$330kNIA NIH HHS RF1 AG084072NIBIB NIH HHS R01 EB028297NIBIB NIH HHS R01 EB032169NIH HHS S10 OD025312NINDS NIH HHS R01 NS114382NINDS NIH HHS R01 NS121040NINDS NIH HHS UF1 NS100614
6 · The paper itselfAbstract
A major challenge for human neuroimaging using functional MRI is the differentiation of neuronal excitation and inhibition which may induce positive and negative BOLD responses. Here we present an innovative multi-contrast laminar functional MRI technique that offers comprehensive and quantitative imaging of neurovascular (CBF, CBV, BOLD) and metabolic (CMRO
Indexed as
Arterial Spin LabelingMesoscopic fMRIMuti-contrast fMRINegative BOLDUltra-high Field (UHF)VASO
Identifiers
PMID39040201
PMCPMC11261924
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