Evidence map›Paper›PMID 39039808›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024

Mitochondrial Transplantation Promotes Protective Effector and Memory CD4

Colwyn A Headley, Shalini Gautam, Angelica Olmo-Fontanez, Andreu Garcia-Vilanova, Varun Dwivedi, Alyssa Schami, Susan Weintraub, Philip S Tsao, Jordi B Torrelles, Joanne Turner

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Mitochondrial Metabolism in T-Cell Exhaustion.International journal of molecular sciences · 2025
    Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Mitochondrial Transplantation Promotes Protective Effector and Memory CD4Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Colwyn A HeadleyHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.ORCID 0000-0001-6041-7615
Shalini GautamHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Angelica Olmo-FontanezPopulation Health Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Andreu Garcia-VilanovaPopulation Health Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Varun DwivediHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Alyssa SchamiPopulation Health Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Susan WeintraubDepartment of Biochemistry & Structural Biology, UT health San Antonio, San Antonio, TX, 78229, USA.
Philip S TsaoStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, 94305, USA.
Jordi B TorrellesPopulation Health Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.
Joanne TurnerHost-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX, 78227, USA.

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Social stress as a co-morbidity of age-associated tuberculosisP01AG051428 · NIA · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI TORRELLES, JORDI B · 2016 to 2020
$9.9M
Interdisciplinary NexGen TB research Advancement Center (IN-TRAC)P30AI168439 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Shannan Hall-Ursone · 2022 to 2026
$6.9M
T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
BD FACSymphonyS10OD028653 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI TURNER, JOANNE · 2020 to 2020
$463k
Elucidate the adverse impact of mitochondria-induced oxidative stress in molecular and cellular determinants in the aging lung, driving susceptibility to Mycobacterium tuberculosis infectionF99AG079802 · NIA · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI OLMO-FONTANEZ, ANGELICA MILAGROS · 2022 to 2022
$38k
Douglass Foundation Graduate Student FellowshipNational Institute on Aging of the National Institutes of Health P01AG051428NHLBI NIH HHS 1T32HL098049NHLBI NIH HHS T32 HL098049NIAID NIH HHS P30 AI168439NIA NIH HHS F99 AG079802NIA NIH HHS P01 AG051428NIH HHS P51 OD011133NIH HHS S10 OD028653NIH/NIA F99/K00 fellowship F99AG079802Office Of The Director, The National Institutes of Health S10OD028653Stanford University Propel Post-Doctoral FellowshipTexas Biomedical Research Institute Interdisciplinary NexGen TB Research Advancement Center (IN-TRAC), an NIH-funded program P30-AI168439The Burroughs Wellcome Fund Postdoctoral Diversity Enrichment Program 1069497The Texas Biomed Research Institute Post-Doctoral Forum GrantWellcome Trust
6 · The paper itself

Abstract

Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb), is a major global health concern, particularly affecting those with weakened immune systems, including the elderly. CD4

Indexed as

CD4-Positive T-LymphocytesDisease Models, AnimalMitochondriaMycobacterium tuberculosisTuberculosisAgedAgingAnimalsCellular SenescenceFemaleHumansMaleMiceMice, Inbred C57BLCD4+ T Cellscellular reprogrammingimmune agingimmunometabolismmitochondrial dysfunctionmitochondrial reprogrammingmitochondrial transplantationoxidative stressT cell exhaustionT cell senescencetuberculosis

Identifiers

PMID39039808
PMCPMC11423092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.