Evidence map›Paper›PMID 39039602›Full record

ArticleTrials2024

The effect of time-restricted eating on arterial stiffness indices in men with metabolic syndrome: study protocol for a randomized controlled trial.

Aliyeh Ghannadzadeh Yazdi, Mohammad Masoumvand, Elena Philippou, Alireza Hatami, Zahra Dehnavi, Hanieh Barghchi, Maryam Ahmadi-Khorram, Ali Jafarzadeh Esfehani, Mohsen Nematy

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aliyeh Ghannadzadeh YazdiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0000-0001-6300-586X
Mohammad MasoumvandDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0009-0003-2617-4711
Elena PhilippouDepartment of Life Sciences, School of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus.ORCID http://orcid.org/0000-0003-0300-9572
Alireza HatamiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0009-0001-8712-0165
Zahra DehnaviDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0000-0003-4926-4229
Hanieh BarghchiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0000-0002-3503-5540
Maryam Ahmadi-KhorramDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran.ORCID http://orcid.org/0009-0008-0850-6934
Ali Jafarzadeh Esfehani *Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran. dr_A_Jafarzadeh@yahoo.com.ORCID http://orcid.org/0000-0002-4185-2694
Mohsen Nematy *Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 91779-48564, Iran. MohsenNematy110@gmail.com.ORCID http://orcid.org/0000-0003-3202-2709

Funding

Mashhad University of Medical Sciences 4001494
6 · The paper itself

Abstract

backgroundTime-restricted eating (TRE) has been shown to be associated with improvements in some aspects of the metabolic syndrome. Nevertheless, only a few studies have addressed the effect of TRE on pulse wave velocity (PWV). We thus propose a randomized controlled trial to compare the effects of TRE with standard dietary advice on PWV and thereby present the protocol.

methodsForty-eight participants will be assigned to either TRE or control groups using simple randomization. The TRE group will consume their meals during a 10-h period and experience 14 h of fasting. They will also be advised to consume their last meal no later than 20:00. Both groups will receive standard dietary advice. The participants will be followed for 6 weeks. The primary outcome will be changes in PWV. Laboratory measurements, including lipid profile, liver enzyme tests, fasting blood glucose (FBG), insulin concentrations, and insulin resistance, as well as anthropometric data, blood pressure, basal metabolic rate, appetite status, physical activity level, sleep quality, cognitive function, quality of life, and calorie intake, will be evaluated throughout the study. DISCUSSION: The outcomes of this study will allow a comparison of the effects of TRE and standard dietary recommendations on PWV and other cardiometabolic factors in individuals with metabolic syndrome (MetS).

trial registrationIranian Registry of Clinical Trials; code: IRCT20201230049889N1; registered on August 14, 2022. The registration of the trial is accessible at: https://www.IRCT.ir/trial/64485?revision=281341 .

Indexed as

FastingMetabolic SyndromePulse Wave AnalysisRandomized Controlled Trials as TopicVascular StiffnessAdultBlood GlucoseHumansIranMaleMiddle AgedTime FactorsTreatment OutcomeBlood GlucoseArterial stiffnessCircadian rhythmIntermittent fastingMetabolic syndromePulse wave velocityRandomized controlled trialTime-restricted eating

Identifiers

PMID39039602
PMCPMC11529165

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.