Evidence map›Paper›PMID 39039375›Full record

ArticleCurrent medical science2024

Prevalence and Risk Factors of Stroke in Inpatients with Type 2 Diabetes Mellitus in China.

Zuo-Ling Xie, Chen-Chen Wang, Xi Huang, Zheng Wang, Hai-Yan Shangguan, Shao-Hua Wang

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Article in Current medical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Zuo-Ling XieDepartment of Endocrinology, the Affiliated ZhongDa Hospital of Southeast University, Nanjing, 210009, China.
Chen-Chen WangDepartment of Endocrinology, the Affiliated ZhongDa Hospital of Southeast University, Nanjing, 210009, China.
Xi HuangDepartment of Endocrinology, the Affiliated ZhongDa Hospital of Southeast University, Nanjing, 210009, China.
Zheng WangSchool of Medicine, Southeast University, Nanjing, 210009, China.
Hai-Yan ShangguanSchool of Medicine, Southeast University, Nanjing, 210009, China.
Shao-Hua WangDepartment of Endocrinology, the Affiliated ZhongDa Hospital of Southeast University, Nanjing, 210009, China. gyjwsh@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe prevalence and the cluster characteristics of risk factors of stroke were assessed in a Chinese diabetic population.

methodsClinical data of 30 693 inpatients who were diagnosed with type 2 diabetes mellitus (T2DM) and admitted between 2013 and 2018 were retrospectively analyzed. The age-standardized prevalence of stroke was estimated using the 2010 Chinese population census data, and risk factors were analyzed by multiple imputation and regression.

resultsThe crude and standardized prevalence rates of stroke in patients with T2DM were 34.4% and 21.5%, respectively, and 85.2% of the stroke patients had ischemic stroke. Nearly half of the patients who experienced stroke had clusters of more than 4 risk factors. Compared with no-risk-factor clustering, the risk of stroke significantly increased 3-4 times in the presence of more than 4 risk-factor clusters (P<0.001). Hypertension was the most common major risk factor for ischemic stroke [odds ratio (OR), 2.34; 95% confidence interval (CI), 2.18-2.50] and hemorrhagic stroke (OR, 3.68; 95% CI 2.95-4.59; P<0.001). Moreover, a 1-standard-deviation increase in fasting blood glucose (FBG) was significantly negatively correlated with ischemic stroke risk, and the same change in FBG was significantly associated with an 8% increased risk of hemorrhagic stroke.

conclusionThe prevalence of stroke in patients with T2DM is rather high, and the clustering of risk factors is associated with the development of stroke in T2DM patients. Risk factors differ in different stroke subtypes. Identifying risk factors for a specific high-risk group is necessary.

Indexed as

Diabetes Mellitus, Type 2StrokeAdultAgedAged, 80 and overBlood GlucoseChinaFemaleHumansHypertensionInpatientsMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsBlood Glucoseclusterprevalencerisk factorstroketype 2 diabetes mellitus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.