Evidence map›Paper›PMID 39039244›Full record

SynthesisScientific reports2024

Hypertension among people living with human immunodeficiency virus in sub-Saharan Africa: a systematic review and meta-analysis.

Alexander Chen, Yih-Kai Chan, Ana O Mocumbi, Dike B Ojji, Laura Waite, Justin Beilby, Jim Codde, Igor Dobe, Benedicta Ngwenchi Nkeh-Chungag, Albertino Damasceno and 1 more

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexander ChenTorrens University Australia, Adelaide, SA, Australia.
Yih-Kai ChanAustralian Catholic University, Melbourne, VIC, Australia.
Ana O MocumbiUniversidade Eduardo Mondlane, Maputo, Mozambique.
Dike B OjjiDepartment of Internal Medicine, Faculty of Clinical Sciences, University of Abuja, Abuja, Nigeria.
Laura WaiteVictorian Department of Health, Melbourne, VIC, Australia.
Justin BeilbyTorrens University Australia, Adelaide, SA, Australia.
Jim CoddeInstitute for Health Research, The University of Notre Dame Australia, 32 Mouat St, Fremantle, WA, 6160, Australia.
Igor DobeUniversidade Eduardo Mondlane, Maputo, Mozambique.
Benedicta Ngwenchi Nkeh-ChungagDepartment of Biological and Environmental Sciences, Faculty of Natural Sciences, Walter Sisulu University, Mthatha, South Africa.
Albertino DamascenoUniversidade Eduardo Mondlane, Maputo, Mozambique.
Simon StewartUniversidade Eduardo Mondlane, Maputo, Mozambique. simon.stewart@nd.edu.au.

Funding

VirologyP30AI036214 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SUSAN JANET LITTLE · 1994 to 2026
$78.4M
National Health and Medical Research Council of Australia GNT1135894NIAID NIH HHS P30 AI036214
6 · The paper itself

Abstract

We performed a systematic review and meta-analysis of hypertension in people living with human immunodeficiency virus (HIV) in sub-Saharan Africa (SSA). We searched the PubMed, Google Scholar, African Index Medicus, and Embase databases to identify studies published from January 1, 2010, to December 31, 2021. We used a random-effects model to estimate the pooled prevalence of hypertension and mean SBP/DBP level on a sex-specific basis. We included 48 studies reporting data on a pooled sample of 193,843 people living with HIV (PLW-HIV) in SSA. The pooled mean SBP/DBP level was 120 (95% CI 113-128)/77 (95%CI 72-82) mmHg, while the overall pooled prevalence of hypertension was 21.9% (95% CI 19.9-23.9%). Further meta-regression analyses suggested that the prevalence of hypertension was 1.33 times greater in males, 1.23 times greater in individuals receiving antiretroviral therapy (ART) and 1.45 times greater in those individuals with a CD4-count ≥ 200. This meta-analysis of the contemporary pattern of BP levels among PLW-HIV in SSA, suggests that around one in five of such individuals also have hypertension. Given the further context of greater access to ART and subsequently greater longevity, study findings support calls to integrate cardiovascular management into routine HIV care.

Indexed as

HIV InfectionsHypertensionAfrica South of the SaharaCD4 Lymphocyte CountFemaleHumansMalePrevalence

Identifiers

PMID39039244
PMCPMC11263367

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.