Evidence map›Paper›PMID 39039239›Full record

ArticleCommunications biology2024

Mediodorsal thalamus and ventral pallidum contribute to subcortical regulation of the default mode network.

Yilei Zhao, Tobias Kirschenhofer, Michael Harvey, Gregor Rainer

Erratum issuedAbstract read
In one paragraph

Article in Communications biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Yilei ZhaoSection of Medicine, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.ORCID 0000-0002-5146-8493
Tobias KirschenhoferSection of Medicine, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Michael HarveySection of Medicine, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland.
Gregor RainerSection of Medicine, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland. gregor.rainer@unifr.ch.ORCID 0000-0002-5805-2220

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (Swiss National Science Foundation) 182504
6 · The paper itself

Abstract

Humans and other animals readily transition from externally to internally focused attention, and these transitions are accompanied by activation of the default mode network (DMN). The DMN was considered a cortical network, yet recent evidence suggests subcortical structures are also involved. We investigated the role of ventral pallidum (VP) and mediodorsal thalamus (MD) in DMN regulation in tree shrew, a close relative of primates. Electrophysiology and deep learning-based classification of behavioral states revealed gamma oscillations in VP and MD coordinated with gamma in anterior cingulate (AC) cortex during DMN states. Cross-frequency coupling between gamma and delta oscillations was higher during DMN than other behaviors, underscoring the engagement of MD, VP and AC. Our findings highlight the importance of VP and MD in DMN regulation, extend homologies in DMN regulation among mammals, and underline the importance of thalamus and basal forebrain to the regulation of DMN.

Indexed as

Basal ForebrainDefault Mode NetworkAnimalsFemaleGyrus CinguliMaleMediodorsal Thalamic NucleusThalamusTupaiidae

Identifiers

PMID39039239
PMCPMC11263694

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.