Evidence map›Paper›PMID 39039181›Full record

ArticleNature cell biology2024

Trafficking circuit of CD8

Rong-Yi Shi, Neng Zhou, Li Xuan, Zhong-Hui Jiang, Jing Xia, Jian-Min Zhu, Kai-Ming Chen, Guo-Li Zhou, Guo-Pan Yu, Jun Zhang and 10 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature cell biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The role of CD8Frontiers in immunology · 2026
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Rong-Yi Shi *Key Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.ORCID http://orcid.org/0000-0001-9712-4146
Neng Zhou *Key Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.
Li Xuan *Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhong-Hui Jiang *Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Jing XiaKey Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.
Jian-Min ZhuKey Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.
Kai-Ming ChenKey Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China.
Guo-Li ZhouShanghai Immune Therapy Institute, Renji Hospital, SJTU-SM, Shanghai, China.
Guo-Pan YuDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China.ORCID http://orcid.org/0000-0002-5732-0318
Jun ZhangDepartment of Biology, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Chuanxin HuangShanghai Institute of Immunology and Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis, Chinese Ministry of Education, Faculty of Basic Medicine, SJTU-SM, Shanghai, China.
Ai-Bin LiangDepartment of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.ORCID http://orcid.org/0000-0002-8978-1987
Kai-Wei LiangDepartment of Pathophysiology, School of Basic Medical Sciences, Wuhan University, Wuhan, China.ORCID http://orcid.org/0000-0002-6021-353X
Hao ZhangDepartment of Cardiothoracic Surgery, Shanghai Children's Medical Center, SJTU-SM, Shanghai, China.
Jian-Feng ChenState Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0002-2892-1691
Dachuan ZhangDepartment of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis, Chinese Ministry of Education, SJTU-SM, Shanghai, China.ORCID http://orcid.org/0000-0002-1746-275X
Yi ZhongShanghai Immune Therapy Institute, Renji Hospital, SJTU-SM, Shanghai, China. zhongyi@sjtu.edu.cn.ORCID http://orcid.org/0000-0003-2294-0995
Qi-Fa LiuDepartment of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China. liuqifa628@163.com.ORCID http://orcid.org/0000-0003-4015-3952
Guo-Qiang ChenSchool of Basic Medicine and Life Science, Hainan Academy of Medical Sciences, Hainan Medical University, Haikou, China. chengq@shsmu.edu.cn.ORCID http://orcid.org/0000-0003-4936-2363
Cai-Wen DuanKey Laboratory of Pediatric Hematology and Oncology in National Health Commission, Pediatric Translational Medicine Institute, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China. caiwenduan@sjtu.edu.cn.ORCID http://orcid.org/0000-0003-2590-3145

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy elicits a systemic antitumour immune response in peripheral circulating T cells. However, the T cell trafficking circuit between organs and their contributions to antitumour immunity remain largely unknown. Here we show in multiple mouse leukaemia models that high infiltration of leukaemic cells in bone marrow (BM) stimulates the transition of CD8

Indexed as

CD8-Positive T-LymphocytesCell MovementMice, Inbred C57BLAnimalsBone MarrowCell Line, TumorHumansIntegrin beta ChainsIntestinal MucosaIntestinesMiceMice, KnockoutReceptors, CXCR3Cxcr3 protein, mouseintegrin beta7Integrin beta ChainsReceptors, CXCR3

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.