ArticleScientific reports2024
Biocompatibility, bioactivity, porosity, and sealer/dentin interface of bioceramic ready-to-use sealers using a dentin-tube model.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The trial behind it
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Who cites it
10 citing papers in PubMed.
- Effect of dentin pre-treatment with Bioglass F18 suspensions on surface characteristics and bond strength of endodontic sealers.Clinical oral investigations · 2026Article
- Filling ability and blooming artifact expression in long-oval root canals: influence of CBCT device, endodontic sealer, and BAR filter.Oral radiology · 2026Article
- Effects of SWEEPS Laser-Activated Irrigation and Diode Laser Irradiation on Void Formation and Bond Strength of a New Premixed Calcium Silicate Sealer, BioRoot Flow-An In Vitro Study.Bioengineering (Basel, Switzerland) · 2026Article
- Effect of F18 Bioactive Glass-Treated Gutta-Percha on Interaction with Endodontic Sealers.Brazilian dental journal · 2026Article
- Effect of dentine moisture conditions on interfacial adaptation of a calcium silicate-based sealer compared with an epoxy resin-based sealer: an SEM/EDX analysis.Biomaterial investigations in dentistry · 2026Article
- Physical and surface analysis of calcium silicate Clinker after acid challenge: a micro-CT and SEM study.Brazilian oral research · 2026Article
- A Micro-Computed Tomography Analysis of Void Formation in Apical Plugs Created with Calcium Silicate-Based Materials Using Various Application Techniques in 3D-Printed Simulated Immature Teeth.Dentistry journal · 2025Article
- Microstructural and Elemental Characterization of Calcium Silicate-Based Sealers.Nanomaterials (Basel, Switzerland) · 2025Article
- Evidence synthesis of postoperative pain with bioceramic vs. epoxy resin sealers: umbrella review of randomized trials within existing systematic reviews.Frontiers in dental medicine · 2025Review
- Physicochemical properties, bond strength, and antibiofilm activity of a powder-gel bioceramic endodontic sealer.Brazilian dental journal · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
This study evaluated the biocompatibility, bioactivity, porosity, and sealer/dentin interface of Sealer Plus BC (SP), Bio-C Sealer (BIOC), TotalFill BC Sealer (TF), and AH Plus (AHP). Dentin tubes filled with the sealers and empty tubes (control group) were implanted in the subcutaneous tissue of rats for different periods (n = 6 per group/period). Number of inflammatory cells (ICs), capsule thickness, von Kossa reaction, interleukin-6 (IL-6) and osteocalcin (OCN) were evaluated. Porosity and voids in the interface dentin/sealers were assessed by micro-computed tomography. The data were submitted to ANOVA/Tukey's tests (α = 0.05). Greater capsule thickness, ICs and IL-6 immunolabeling cells were observed in AHP. No significant difference in thickness of capsule, ICs, and IL-6- immunolabeling cells was detected between SP and TF, in all periods, and after 30 and 60 days between all groups. At 60 days all groups had reduction in capsule thickness, ICs and IL-6 immunolabeling cells. Von Kossa-positive and birefringent structures were observed in the capsules around the sealers. BIOC, SP, and TF exhibited OCN-immunolabeling cells. All sealers had porosity values below 5%, besides low and similar interface voids. BIOC, SP and TF are biocompatible, bioactive, and have low porosity and voids. The dentin-tube model used is an alternative for evaluating bioceramic materials.
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Registered trials
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