Evidence map›Paper›PMID 39039059›Full record

ArticleNature communications2024

Soft jamming of viral particles in nanopores.

Léa Chazot-Franguiadakis, Joelle Eid, Gwendoline Delecourt, Pauline J Kolbeck, Saskia Brugère, Bastien Molcrette, Marius Socol, Marylène Mougel, Anna Salvetti, Vincent Démery and 5 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Léa Chazot-FranguiadakisLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Joelle EidInstitut de Recherche en Infectiologie de Montpellier, UMR CNRS 9004, Université de Montpellier, Montpellier, France.
Gwendoline DelecourtInstitut Parisien de Chimie Moléculaire, UMR CNRS 8232, Sorbonne Université, Paris, France.
Pauline J KolbeckLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Saskia BrugèreLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Bastien MolcretteLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Marius SocolInstitut de Recherche en Infectiologie de Montpellier, UMR CNRS 9004, Université de Montpellier, Montpellier, France.
Marylène MougelInstitut de Recherche en Infectiologie de Montpellier, UMR CNRS 9004, Université de Montpellier, Montpellier, France.ORCID 0000-0002-0345-1427
Anna SalvettiCentre International de Recherche en Infectiologie, UMR CNRS 5308, Université de Lyon, INSERM, Lyon, France.
Vincent DémeryLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Jean-Christophe LacroixUniversité Paris Cité, ITODYS, CNRS, F-75006, Paris, France.ORCID 0000-0002-7024-4452
Véronique BennevaultInstitut Parisien de Chimie Moléculaire, UMR CNRS 8232, Sorbonne Université, Paris, France.
Philippe GuéganInstitut Parisien de Chimie Moléculaire, UMR CNRS 8232, Sorbonne Université, Paris, France.
Martin CastelnovoLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France.
Fabien MontelLaboratoire de Physique, UMR CNRS 5672, ENS de Lyon, Université de Lyon, Lyon, France. fabien.montel@ens-lyon.fr.ORCID 0000-0001-5430-864X

Funding

Centre National de la Recherche Scientifique (National Center for Scientific Research) 80 Prime NanoViro
6 · The paper itself

Abstract

Viruses have remarkable physical properties and complex interactions with their environment. However, their aggregation in confined spaces remains unexplored, although this phenomenon is of paramount importance for understanding viral infectivity. Using hydrodynamical driving and optical detection, we developed a method to detect the transport of single virus in real time through synthetic nanopores. We unveiled a jamming phenomenon specifically associated with virus confinement under flow. We showed that the interactions of viral particles with themselves and with the pore surface were critical for clog formation. Based on the detailed screening of the physical and chemical determinants, we proposed a simple dynamical model that recapitulated all the experimental observations. Our results pave the way for the study of jamming phenomena in the presence of more complex interactions.

Indexed as

NanoporesVirionHydrodynamics

Identifiers

PMID39039059
PMCPMC11263580

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.