ArticleThe Plant cell2024
GIBBERELLIN PERCEPTION SENSOR 2 reveals genesis and role of cellular GA dynamics in light-regulated hypocotyl growth.
Article in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026Review
- Cell-type specific early perception of nine phytohormones revealed by single-nucleus transcriptomics in Arabidopsis.Nature communications · 2026Article
- Evolutionary shifts in plant adaptation mediated by phytohormones.Plant communications · 2026Review
- The genomic basis of local adaptation to photoperiod across altitude in a self-fertilizing monkeyflower.bioRxiv : the preprint server for biology · 2026Article
- Article
- A balance of metabolism and diffusion articulates a gibberellin hormone gradient in theProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Comparing hormone dynamics in cereal crops via transient expression of hormone sensors.Plant & cell physiology · 2025Article
- Estimating Radicle Length of Germinating Elm Seeds via Deep Learning.Sensors (Basel, Switzerland) · 2025Article
- Gibberellin-deactivating GA2OX enzymes act as a hub for auxin-gibberellin cross talk inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Induction of α-amylase and endosperm-imposed seed dormancy: two pioneering papers in gibberellin research.Planta · 2025Review
- Gibberellin-mediated internode elongation in grasses with a focus on bamboo: molecular pathways and regulatory networks.Frontiers in plant science · 2025Review
- Seeing hormones in action: High-resolution gibberellin dynamics in nodules.The Plant cell · 2024Article
- Gibberellin dynamics governing nodulation revealed using GIBBERELLIN PERCEPTION SENSOR 2 in Medicago truncatula lateral organs.The Plant cell · 2024Article
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Authors and funding
5 authors.
Funding
Abstract
The phytohormone gibberellic acid (GA) is critical for environmentally sensitive plant development including germination, skotomorphogenesis, and flowering. The Förster resonance energy transfer biosensor GIBBERELLIN PERCEPTION SENSOR1, which permits single-cell GA measurements in vivo, has been used to observe a GA gradient correlated with cell length in dark-grown, but not light-grown, hypocotyls. We sought to understand how light signaling integrates into cellular GA regulation. Here, we show how the E3 ligase CONSTITUTIVE PHOTOMORPHOGENESIS1 (COP1) and transcription factor ELONGATED HYPOCOTYL 5 (HY5) play central roles in directing cellular GA distribution in skoto- and photomorphogenic hypocotyls, respectively. We demonstrate that the expression pattern of the GA biosynthetic enzyme gene GA20ox1 is the key determinant of the GA gradient in dark-grown hypocotyls and is a target of COP1 signaling. We engineered a second generation GPS2 biosensor with improved orthogonality and reversibility. GPS2 revealed a previously undetectable cellular pattern of GA depletion during the transition to growth in the light. This GA depletion partly explains the resetting of hypocotyl growth dynamics during photomorphogenesis. Achieving cell-level resolution has revealed how GA distributions link environmental conditions with morphology and morphological plasticity. The GPS2 biosensor is an ideal tool for GA studies in many conditions, organs, and plant species.
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