Evidence map›Paper›PMID 39038916›Full record

ArticleBMJ open respiratory research2024

Use of oral moist tobacco (snus) in puberty and its association with asthma in the population-based RHINESSA study.

Juan Pablo López-Cervantes, Vivi Schlünssen, Chamara Senaratna, Simone Accordini, Francisco Javier Callejas, Karl A Franklin, Mathias Holm, Nils Oskar Jogi, Andrei Malinovschi, Anna Oudin and 5 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Juan Pablo López-CervantesDepartment of Global Public Health and Primary Care, Centre for International Health, University of Bergen Faculty of Medicine and Dentistry, Bergen, Norway juan.cervantes@uib.no.ORCID http://orcid.org/0000-0002-4668-911X
Vivi SchlünssenDepartment of Public Health, Research Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Chamara SenaratnaAllergy and Lung Health Unit, Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne VCCC, Victoria, Melbourne, Australia.
Simone AccordiniUnit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy.ORCID http://orcid.org/0000-0003-1510-6193
Francisco Javier CallejasDepartment of Respiratory Medicine, Albacete University Hospital Complex, Albacete, Spain.
Karl A FranklinDepartment of Surgical and Perioperative Sciences, Surgery, Umeå University, Umea, Sweden.ORCID http://orcid.org/0000-0002-5306-1697
Mathias HolmDepartment of Occupational and Environmental Medicine, Sahlgrenska University Hospital, Goteborg, Sweden.
Nils Oskar JogiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.
Andrei MalinovschiDepartment of Medical Sciences, Clinical Physiology, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0002-4098-7765
Anna OudinDepartment of Public Health and Clinical Medicine, Umeå University, Umea, Sweden.
Torben SigsgaardDepartment of Public Health, Research Unit for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Elin Helga ThorarinsdottirPrimary Health Care of the Capital Area, Reykjavik, Iceland.ORCID http://orcid.org/0000-0001-6561-3746
Christer JansonDepartment of Medical Sciences: Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-5093-6980
Randi Jacobsen Bertelsen *Department of Clinical Science, University of Bergen, Bergen, Norway.
Cecilie Svanes *Department of Global Public Health and Primary Care, Centre for International Health, University of Bergen Faculty of Medicine and Dentistry, Bergen, Norway.ORCID http://orcid.org/0000-0001-8512-5192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the association of early snus use initiation (≤15 years of age) with asthma and asthma symptoms.

designCross-sectional analysis of a population-based cohort.

settingStudy centres in Norway, Sweden, Iceland, Denmark and Estonia, from 2016 to 2019.

participants9002 male and female participants above 15 years of age of the Respiratory Health in Northern Europe, Spain and Australia study.

main outcome measuresCurrent asthma and asthma symptoms.

resultsThe median age of study participants was 28 years (range 15-53) and 58% were women. 20% had used snus, 29% men and 14% women. Overall, 26% of males and 14% of females using snus started ≤15 years of age. Early snus use initiation was associated with having three or more asthma symptoms (OR 2.70; 95% CI 1.46 to 5.00) and a higher asthma symptom score (β-coefficient (β) 0.35; 95% CI 0.07 to 0.63) in women. These associations were weak in men (OR 1.23; 95% CI 0.78 to 1.94; β 0.16; 95% CI -0.06 to 0.38, respectively). There was evidence for an association of early snus initiation with current asthma (OR 1.72; 95% CI 0.88 to 3.37 in women; OR 1.31; 95% CI 0.84 to 2.06 in men). A sensitivity analysis among participants without smoking history showed stronger estimates for all three outcomes, in both men and women, statistically significant for three or more asthma symptoms in women (OR 3.28; 95% CI 1.18 to 9.10). Finally, no consistent associations with asthma outcomes were found for starting snus after age 15 years.

conclusionsSnus initiation in puberty was associated with higher likelihood of asthma and asthma symptoms, with the highest estimates in females and those without smoking history. These results raise concerns about the health adversities of early snus initiation and emphasise the need for public health initiatives to protect young people from this tobacco product.

Indexed as

AsthmaTobacco, SmokelessAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPubertyYoung AdultAsthmaAsthma EpidemiologySurveys and QuestionnairesTobacco and the lung

Identifiers

PMID39038916
PMCPMC11268032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.