Evidence map›Paper›PMID 39038084›Full record

ArticleBrazilian journal of cardiovascular surgery2024

Sutureless Aortic Valve Replacement vs. Transcatheter Aortic Valve Implantation in Patients with Small Aortic Annulus: Clinical and Hemodynamic Outcomes from a Multi-Institutional Study.

Lorenzo Di Bacco, Michele D'Alonzo, Marco Di Eusanio, Fabrizio Rosati, Marco Solinas, Massimo Baudo, Thierry Folliguet, Stefano Benussi, Theodor Fischlein, Claudio Muneretto

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in Brazilian journal of cardiovascular surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. TAVI vs SAVR: The timeless showdown in aortic valve replacement.International journal of cardiology. Heart & vasculature · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lorenzo Di BaccoDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Michele D'AlonzoDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.ORCID 0000-0002-3971-4145
Marco Di EusanioCardiovascular Surgery Department, Ospedali Riuniti, Ancona, Italy.
Fabrizio RosatiDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Marco SolinasDepartment of Adult Cardiac Surgery, G. Pasquinucci Heart Hospital, Massa, Italy.
Massimo BaudoDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Thierry FolliguetCardiac surgery, Centre Hospitalier Universitaire Mondor, Créteil, France.
Stefano BenussiDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.
Theodor FischleinDepartment of Cardiac Surgery, Klinikum Nürnberg, Nuremberg, Germany.
Claudio MunerettoDepartment of Cardiac Surgery, ASST Spedali Civili di Brescia, University of Brescia, Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to compare hemodynamic performances and clinical outcomes of patients with small aortic annulus (SAA) who underwent aortic valve replacement by means of sutureless aortic valve replacement (SUAVR) or transcatheter aortic valve implantation (TAVI).

methodsFrom 2015 to 2020, 622 consecutive patients with SAA underwent either SUAVR or TAVI. Through a 1:1 propensity score matching analysis, two homogeneous groups of 146 patients were formed. Primary endpoint: all cause-death at 36 months. Secondary endpoints: incidence of moderate to severe patient-prosthesis mismatch (PPM) and incidence of major adverse cardiovascular and cerebrovascular events (MACCEs).

resultsAll-cause death at three years was higher in the TAVI group (SUAVR 12.2% vs. TAVI 21.0%, P=0.058). Perioperatively, comparable hemodynamic performances were recorded in terms of indexed effective orifice area (SUAVR 1.12 ± 0.23 cm2/m2 vs. TAVI 1.17 ± 0.28 cm2/m2, P=0.265), mean transvalvular gradients (SUAVR 12.9 ± 5.3 mmHg vs. TAVI 12.2 ± 6.2 mmHg, P=0.332), and moderate-to-severe PPM (SUAVR 4.1% vs. TAVI 8.9%, P=0.096). TAVI group showed a higher cumulative incidence of MACCEs at 36 months (SUAVR 18.1% vs. TAVI 32.6%, P<0.001). Pacemaker implantation (PMI) and perivalvular leak ≥ 2 were significantly higher in TAVI group and identified as independent predictors of mortality (PMI: hazard ratio [HR] 3.05, 95% confidence interval [CI] 1.34-6.94, P=0.008; PPM: HR 2.72, 95% CI 1.25-5.94, P=0.012).

conclusionIn patients with SAA, SUAVR and TAVI showed comparable hemodynamic performances. Moreover, all-cause death and incidence of MACCEs at follow-up were significantly higher in TAVI group.

Indexed as

Aortic ValveAortic Valve StenosisHemodynamicsPropensity ScoreTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansMalePostoperative ComplicationsRetrospective StudiesRisk FactorsSutureless Surgical ProceduresAorta ValveHemodynamicsPropensity ScoresProstheses and ImplantsTranscatheter Aortic Valve Replacement

Identifiers

PMID39038084
PMCPMC11259373

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.