Evidence map›Paper›PMID 39037980›Full record

ArticlePloS one2024

Physical therapy for muscle strengthening in individuals with amyotrophic lateral sclerosis: A protocol for a systematic review and meta-analysis.

Aline Alves de Souza, Stephano Tomaz da Silva, Lorenna Raquel Dantas de Macedo, Diogo Neres Aires, Karen de Medeiros Pondofe, Luciana Protásio de Melo, Ricardo Alexsandro de Medeiros Valentim, Tatiana Souza Ribeiro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aline Alves de SouzaDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.ORCID 0000-0002-4424-3034
Stephano Tomaz da SilvaDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Lorenna Raquel Dantas de MacedoDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Diogo Neres AiresDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Karen de Medeiros PondofeDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Luciana Protásio de MeloLaboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Ricardo Alexsandro de Medeiros ValentimLaboratory of Technological Innovation in Health, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Tatiana Souza RibeiroDepartment of Physical Therapy, Federal University of Rio Grande do Norte, Natal, RN, Brazil.ORCID 0000-0002-9611-1076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeople with Amyotrophic Lateral Sclerosis (ALS) can present initially muscle weakness, which is a debilitating symptom that may be improved by engaging in muscle strengthening activities. Currently, the effects of motor interventions for muscle strengthening in people with ALS are unclear. This review intends to analyze the effects of motor interventions for muscle strengthening in individuals with ALS. METHODS AND ANALYSIS: Randomized, non-randomized, and quasi-experimental clinical trials assessing individuals with ALS of both sexes, aged 18 years or older, who have received motor interventions for muscle strengthening considering all practices that can lead to increased strength, endurance, power and muscular hypertrophy will be included. No restriction on language, location, or publication date will be applied. MEDLINE, EMBASE, Cochrane Library (CENTRAL), SPORTDiscus, and Physiotherapy Evidence Database (PEDro) databases will be searched. The US National Institutes of Health Ongoing, ClinicalTrials.gov, and the reference lists of included studies will also be searched. Two reviewers will independently screen titles and abstracts and extract data from included studies. The methodological quality of the included studies will be assessed by the PEDro scale and the certainty of the evidence by the GRADE approach. Disagreements will be resolved by a third researcher. Findings will be presented in text and table formats. A meta-analysis will compare the effects of motor interventions for muscle strengthening versus placebo or other interventions.

Indexed as

Amyotrophic Lateral SclerosisMeta-Analysis as TopicMuscle StrengthSystematic Reviews as TopicFemaleHumansMalePhysical Therapy Modalities

Identifiers

PMID39037980
PMCPMC11262630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.