Evidence map›Paper›PMID 39037239›Full record

ArticleAntimicrobial agents and chemotherapy2024

A picomolar inhibitor of the

Stephanie Kabeche, Thomas Braukmann, Jon Doenier, Thomas Meister, Ellen Yeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A fast-acting inhibitor of blood-stagebioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie KabecheDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0002-6808-5835
Thomas BraukmannDepartment of Pathology, Stanford University School of Medicine, Stanford, California, USA.
Jon DoenierDepartment of Biochemistry, Stanford University School of Medicine, Stanford, California, USA.
Thomas MeisterDepartment of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0001-9743-8110
Ellen YehDepartment of Pathology, Stanford University School of Medicine, Stanford, California, USA.ORCID 0000-0003-3974-3816

Funding

INSTITUTIONAL TRAINING GRANT IN GENOME SCIENCET32HG000044 · NHGRI · STANFORD UNIVERSITY · PI MICHAEL P. SNYDER · 1995 to 2026
$32.2M
Harnessing the Unique Biogenesis of the Apicomplexan plastid organelle forAntimalarial TargetsR01AI141366 · NIAID · STANFORD UNIVERSITY · PI YEH, ELLEN · 2019 to 2023
$2.9M
Burroughs Wellcome Fund (BWF)Chan Zuckerberg Initiative (CZI)HHS | National Institutes of Health (NIH) 5T32HG000044HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) 1R01AI141366NHGRI NIH HHS T32 HG000044NIAID NIH HHS R01 AI141366Wellcome Trust
6 · The paper itself

Abstract

We identified MMV026468 as a picomolar inhibitor of blood-stage

Indexed as

AntimalarialsPlasmodium falciparumDrug ResistanceErythritolHemiterpenesHumansOrganophosphorus CompoundsAntimalarialsErythritolHemiterpenesisopentenyl pyrophosphateOrganophosphorus Compoundsantimalarial agentsapicoplastdrug discoveryisoprenoid biosythesismalariaMEP pathway

Identifiers

PMID39037239
PMCPMC11304725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.