Evidence map›Paper›PMID 39036677›Full record

ArticleAsian journal of transfusion science

Is neutropenic fever an obstacle to effective stem cell harvesting?

Semih Başcı, Ersin Bozan, Samet Yaman, Bahar Uncu Ulu, Mehmet Bakırtaş, Tuğçe Nur Yiğenoğlu, Ali Kılınç, Nurgül Özcan, Mehmet Sinan Dal, Merih Kızıl Çakar and 1 more

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Article in Asian journal of transfusion science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Semih BaşcıDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Ersin BozanDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Samet YamanDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Bahar Uncu UluDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Mehmet BakırtaşDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Tuğçe Nur YiğenoğluDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Ali KılınçDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Nurgül ÖzcanDepartment of Clinical Biochemistry, Ankara Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital, University of Health Sciences, Ankara, Turkey.
Mehmet Sinan DalDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Merih Kızıl ÇakarDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.
Fevzi AltuntaşDepartment of Hematology and Bone Marrow Transplantation Center, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAutologous stem cell transplantation (ASCT) is a well-established consolidation treatment for many hematologic cancers which delivers prolonged survival. A subset of patients' adequate stem cell harvest is not achievable with a solitary use of granulocyte colony-stimulating agents (G-CSF). Generally, chemomobilization is employed for patients failing G-CSF and its most feared complication febrile neutropenia (FN). MATERIALS AND

methodsHere, we aimed to investigate the impact of the FN in chemomobilization on apheresis outcomes and engraftment. One hundred and eighty-three patients with the diagnosis of lymphoma or myeloma who underwent chemomobilization between 2015 and 2020 were included in the study.

resultsForty-three patients experienced FN. All patients received G-CSF. All myeloma patients were mobilized with 4 g/m

conclusionHarvesting sufficient CD34+ HSCs from patients with FN is still feasible; however, FN treatment should begin promptly, and further apheresis sessions may be required.

Indexed as

Autologous stem cell transplantationchemomobilizationfebrile neutropenianeutropenic feverstem cell mobilization

Identifiers

PMID39036677
PMCPMC11259352

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.