Evidence map›Paper›PMID 39036638›Full record

ArticleFrontiers in neurology2024

Association between enlarged perivascular spaces in basal ganglia and cerebral perfusion in elderly people.

Simeng Wang, Shuna Yang, Dong Liang, Wei Qin, Lei Yang, Xuanting Li, Wenli Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Simeng Wang *Department of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Shuna Yang *Department of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Dong LiangDepartment of Neurology, Affiliated Hospital of Heze Medical College, Heze, Shandong, China.
Wei QinDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Lei YangDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Xuanting LiDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Wenli HuDepartment of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Enlarged perivascular spaces in basal ganglia (BG-EPVS) are considered an imaging marker of cerebral small vessel disease (CSVD), but its pathogenesis and pathophysiological process remain unclear. While decreased cerebral perfusion is linked to other CSVD markers, the relationship between BG-EPVS and cerebral perfusion remains ambiguous. This study aimed to explore this association. Methods: Elderly individuals with severe BG-EPVS ( Results: There were no significant differences in MTT, TMAX, or CBF between BG-EPVS group and control group. CBV was significantly lower in the BG-EPVS group ( Conclusion: Severe BG-EPVS is an independent risk factor for decreased CBV in the elderly, however, the formation of BG-EPVS is not solely dependent on changes in CBV in this region. This finding provides information about the pathophysiological consequence caused by severe BG-EPVS.

Indexed as

cerebral blood volumecerebral perfusioncerebral small vascular diseaseCT perfusion imagingenlarged perivascular spaces

Identifiers

PMID39036638
PMCPMC11259966

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.