Evidence map›Paper›PMID 39036486›Full record

ArticleCurrent opinion in physiology2020

Sodium channels and transporters in the myometrium.

Chinwendu Amazu, Juan J Ferreira, Celia M Santi, Sarah K England

Abstract read
In one paragraph

Article in Current opinion in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Uterine contractions in rodent models and humans.Acta physiologica (Oxford, England) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chinwendu AmazuDepartment of Obstetrics and Gynecology, Washington University School of Medicine. St Louis. MO.
Juan J FerreiraDepartment of Obstetrics and Gynecology, Washington University School of Medicine. St Louis. MO.
Celia M SantiDepartment of Obstetrics and Gynecology, Washington University School of Medicine. St Louis. MO.
Sarah K EnglandDepartment of Obstetrics and Gynecology, Washington University School of Medicine. St Louis. MO.

Funding

A NOVEL MOLECULAR MECHANISM FOR STIMULATING UTERINE CONTRACTILITY BY OXYTOCINR01HD088097 · NICHD · WASHINGTON UNIVERSITY · PI Sarah K. England, Celia M Santi · 2016 to 2026
$4.1M
Signaling Mechanisms in Myometrial Cells that Modulate Na+ Leak Channel Non-Selective (NALCN) during Pregnancy and LaborF30HD095591 · NICHD · WASHINGTON UNIVERSITY · PI AMAZU, CHINWENDU · 2018 to 2021
$156k
NICHD NIH HHS F30 HD095591NICHD NIH HHS R01 HD088097
6 · The paper itself

Abstract

In excitable cells such as neurons and cardiomyocytes, sodium influx across the plasma membrane contributes to the resting membrane potential, and sodium is the key ion for generating action potentials. In myometrial smooth muscle cells, however, the functions of sodium influx have not been fully elucidated. This review briefly discusses the contribution of Na

Identifiers

PMID39036486
PMCPMC11259238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.