Evidence map›Paper›PMID 39036436›Full record

ArticleNeuro-oncology advances

Neoadjuvant combination treatment with checkpoint inhibitors, chemotherapy, and BRAF/MEK inhibitors for BRAF

Naveed Wagle, Akanksha Sharma, Minhdan Nguyen, Judy Truong, Tiffany M Juarez, Santosh Kesari

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. RAS/MAPK inhibition in pediatric gliomas.Neuro-oncology advances · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naveed WaglePacific Neuroscience Institute, Saint John's Cancer Institute, Providence Saint John's Health Center, Saint Monica, California, USA.
Akanksha SharmaPacific Neuroscience Institute, Saint John's Cancer Institute, Providence Saint John's Health Center, Saint Monica, California, USA.
Minhdan Nguyen
Judy TruongPacific Neuroscience Institute, Saint John's Cancer Institute, Providence Saint John's Health Center, Saint Monica, California, USA.
Tiffany M JuarezPacific Neuroscience Institute, Saint John's Cancer Institute, Providence Saint John's Health Center, Saint Monica, California, USA.ORCID https://orcid.org/0000-0002-1736-9774
Santosh KesariPacific Neuroscience Institute, Saint John's Cancer Institute, Providence Saint John's Health Center, Saint Monica, California, USA.ORCID https://orcid.org/0000-0003-3772-6000

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiation's confounding and adverse effects on tumor microenvironment and normal brain could potentially be delayed by upfront combination treatment. We present a patient with newly diagnosed

Indexed as

BRAFV600Ecase reportcheckpoint inhibitorsglioblastomaneoadjuvant

Identifiers

PMID39036436
PMCPMC11259949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.