Evidence map›Paper›PMID 39036424›Full record

ArticleInternational journal of cardiology. Heart & vasculature2024

Association between obesity and statin use on mortality and hospital encounters in atrial fibrillation.

Michael C Hill, Noah Kim, William Galanter, Ben S Gerber, Colin C Hubbard, Dawood Darbar, Mark D McCauley

Abstract read
In one paragraph

Article in International journal of cardiology. Heart & vasculature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Recent highlights from theInternational journal of cardiology. Heart & vasculature · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michael C HillDivision of Cardiology, College of Medicine, University of Illinois at Chicago, United States.
Noah KimDivision of Cardiology, College of Medicine, University of Illinois at Chicago, United States.
William GalanterDivision of Academic Internal Medicine, College of Medicine, University of Illinois at Chicago, United States.
Ben S GerberDivision of Health Informatics and Implementation Science, Department of Population and Quantitative Health Sciences, University of Massachusetts, United States.
Colin C HubbardDivision of Hospital Medicine, University of California San Francisco, United States.
Dawood DarbarDivision of Cardiology, College of Medicine, University of Illinois at Chicago, United States.
Mark D McCauleyDivision of Cardiology, College of Medicine, University of Illinois at Chicago, United States.

Funding

Myosin Light Chain Dephosphorylation by PPP1R12C Promotes Atrial Hypocontractility and Atrial FibrillationR01HL151508 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCCAULEY, MARK D · 2020 to 2024
$3.2M
NHLBI NIH HHS R01 HL151508
6 · The paper itself

Abstract

Background: Obesity increases risk of atrial fibrillation (AF) at least in part due to pro-inflammatory effects, but has been paradoxically associated with improved mortality. Although statins have pleiotropic anti-inflammatory properties, their interaction with obesity and clinical outcomes in AF is unknown. We explored the relationship between BMI, statin use, and all-cause mortality and AF/congestive heart failure (CHF)-related encounters, hypothesizing that statin exposure may be differentially associated with improved outcomes in overweight/obesity. Methods: This was a single center retrospective cohort study of adults with AF diagnosed between 2011-2018. Patients were grouped by body mass index (BMI) and statin use at time of AF diagnosis. Outcomes included all-cause mortality and ED or inpatient encounters for AF or CHF. Results and Conclusions: A total of 2503 subjects were included (median age 66 years, 43.4 % female, median BMI 29.8 kg/m

Indexed as

Atrial fibrillationHospitalizationMortalityObesityStatins

Identifiers

PMID39036424
PMCPMC11260021

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.