Evidence map›Paper›PMID 39036176›Full record

ReviewCureus2024

Ablation Compared to Pharmacological Treatment for the Reduction of Atrial Fibrillation Recurrence: A Meta-Analysis.

Alan D Kaye, Nicholas T Jones, Tyler Tran, Munira E Khaled, Sean Tilmon, Michael Lieu, Joseph Drinkard, Yair Lopez Torres, Edwin Herron, Shahab Ahmadzadeh and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alan D KayeDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Nicholas T JonesDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Tyler TranDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Munira E KhaledDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Sean TilmonDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Michael LieuDepartment of Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.
Joseph DrinkardDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Yair Lopez TorresDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Edwin HerronDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Shahab AhmadzadehDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Sahar ShekoohiDepartment of Anesthesiology, Louisiana State University Health Sciences Center, Shreveport, USA.
Giustino VarrassiDepartment of Pain Medicine, Paolo Procacci Foundation, Rome, ITA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is one of the most common heart arrhythmias, and due to its variable presentation, detecting and treating AF appropriately can reduce some of its serious complications. Among treatment options, surgical ablation and antiarrhythmic drug therapy are two of the most widely used choices. A systematic review and meta-analysis were conducted to examine the rates of AF recurrence in those treated with ablation compared to pharmacological treatment. Google Scholar and PubMed were searched for study trials published within the last decade that calculated the recurrence of AF symptoms in patient groups that received ablation or pharmacological treatment. Selected studies were analyzed in RevMan 5.4 software (The Cochrane Collaboration, London, England, UK), and each study's odds ratio and overall odds ratio were calculated using a 95% confidence interval. A total of seven studies with 2324 patients were analyzed for the meta-analysis, with 1162 patients receiving ablation and 1162 patients receiving pharmacological treatment. There was a statistically significant decrease in the recurrence of AF in the ablation group compared to the pharmacological treatment group, with a pooled odds ratio of 0.24 (CI 95% 0.14-0.39). AF treated with ablation was more effective in reducing AF recurrence than general pharmacological treatment.

Indexed as

ablationafarrhythmiasatrial fibrillationmedication

Identifiers

PMID39036176
PMCPMC11259506

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.